Investigation on the cellular mechanism of Prunetin evidenced through next generation sequencing and bioinformatic approaches against gastric cancer

Investigation on the cellular mechanism of Prunetin evidenced through next generation sequencing and bioinformatic approaches against gastric cancer

Abstract Gastric cancer is the common type of malignancy positioned at second in mortality rate causing burden worldwide with increasing treatment options. More accurate and reliable diagnostic methods/biomarkers are urgently needed. The application of transcriptomics technologies possesses the high...

Full description

Bibliographic Details
Main Authors:	Preethi Vetrivel, Santhi Nachimuthu, Abusaliya Abuyaseer, Pritam Bhagwan Bhosale, Sang Eun Ha, Hun Hwan Kim, Min Young Park, Gon Sup Kim
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-07-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-022-15826-y

Similar Items

Compound Prunetin Induces Cell Death in Gastric Cancer Cell with Potent Anti-Proliferative Properties: In Vitro Assay, Molecular Docking, Dynamics, and ADMET Studies
by: Preethi Vetrivel, et al.
Published: (2020-07-01)

Comprehensive analysis of Apigetrin's effects on liver cancer cells: Insights from bioinformatics, in vitro studies, and next-generation transcriptome sequencing
by: Pritam Bhagwan Bhosale, et al.
Published: (2025-02-01)

Transcriptome analysis revealed the genes and major pathways involved in prunetrin treated hepatocellular carcinoma cells
by: Abuyaseer Abusaliya, et al.
Published: (2024-11-01)

Apigetrin Abrogates Lipopolysaccharide-Induced Inflammation in L6 Skeletal Muscle Cells through NF-κB/MAPK Signaling Pathways
by: Sang-Eun Ha, et al.
Published: (2022-06-01)

Iridin Induces G2/M Phase Cell Cycle Arrest and Extrinsic Apoptotic Cell Death through PI3K/AKT Signaling Pathway in AGS Gastric Cancer Cells
by: Pritam-Bhagwan Bhosale, et al.
Published: (2021-05-01)

Apigetrin Promotes TNFα-Induced Apoptosis, Necroptosis, G2/M Phase Cell Cycle Arrest, and ROS Generation through Inhibition of NF-κB Pathway in Hep3B Liver Cancer Cells
by: Pritam Bhagwan Bhosale, et al.
Published: (2022-09-01)

Scutellarein Inhibits LPS-Induced Inflammation through NF-κB/MAPKs Signaling Pathway in RAW264.7 Cells
by: Min Yeong Park, et al.
Published: (2022-06-01)

Potential Joint Protective and Anti-Inflammatory Effects of Integrin α<sub>v</sub>β<sub>3</sub> in IL-1β-Treated Chondrocytes Cells
by: Hun Hwan Kim, et al.
Published: (2023-10-01)

Inhibition of Cell Proliferation and Cell Death by Apigetrin through Death Receptor-Mediated Pathway in Hepatocellular Cancer Cells
by: Pritam Bhagwan Bhosale, et al.
Published: (2023-07-01)

Antioxidant effects of phenolic compounds in through the distillation of Lonicera japonica & Chenpi extract and anti-inflammation on skin keratinocyte
by: Hun Hwan Kim, et al.
Published: (2023-11-01)

Publisher Correction: Antioxidant effects of phenolic compounds in through the distillation of Lonicera japonica & Chenpi extract and anti-inflammation on skin keratinocyte
by: Hun Hwan Kim, et al.
Published: (2024-06-01)

Author Correction: Antioxidant effects of phenolic compounds in through the distillation of Lonicera japonica & Chenpi extract and anti-inflammation on skin keratinocyte
by: Hun Hwan Kim, et al.
Published: (2024-02-01)

Author Correction: Antioxidant effects of phenolic compounds in through the distillation of Lonicera japonica & Chenpi extract and anti-inflammation on skin keratinocyte
by: Hun Hwan Kim, et al.
Published: (2023-12-01)

Potential Antioxidant and Anti-Inflammatory Effects of <i>Lonicera japonica</i> and <i>Citri Reticulatae Pericarpium</i> Polyphenolic Extract (LCPE)
by: Se Hyo Jeong, et al.
Published: (2023-08-01)

<i>Pseudomonas aeruginosa</i> Biofilm Formation and Its Control
by: Aishwarya Vetrivel, et al.
Published: (2021-10-01)

Author Correction: Binding affinity screening of polyphenolic compounds in Stachys affinis extract (SAE) for their potential antioxidant and anti-inflammatory effects
by: Hun Hwan Kim, et al.
Published: (2025-01-01)

Binding affinity screening of polyphenolic compounds in Stachys affinis extract (SAE) for their potential antioxidant and anti-inflammatory effects
by: Hun Hwan Kim, et al.
Published: (2024-08-01)

Assessment of Anti-Inflammatory and Antioxidant Effects of <i>Citrus unshiu</i> Peel (CUP) Flavonoids on LPS-Stimulated RAW 264.7 Cells
by: Adhimoolam Karthikeyan, et al.
Published: (2021-10-01)

Prunetin alleviates dextran sulfate sodium-induced colitis via the regulation of inflammatory response based on network pharmacology and experimental evidence
by: Ludi Fan, et al.
Published: (2023-12-01)

Inhibition of Melanogenesis via Passive Immune Targeted Alpha-MSH Binder Polypeptide
by: Se-Hyo Jeong, et al.
Published: (2025-01-01)

Prunetin 4′-<i>O</i>-Phosphate, a Novel Compound, in RAW 264.7 Macrophages Exerts Anti-Inflammatory Activity via Suppression of MAP Kinases and the NFκB Pathway
by: Tae-Jin Park, et al.
Published: (2021-11-01)

Sinensetin regulates age-related sarcopenia in cultured primary thigh and calf muscle cells
by: Jin-A Kim, et al.
Published: (2019-10-01)

Evidenced-based handbook of neonatology /
by: Oh, William
Published: (c201)

Evidencing creativity in educational settings
by: Jonathan Heard, et al.
Published: (2023-04-01)

Next-generation bioinformatics in dermatology research
by: Yi-Ju Chen
Published: (2022-01-01)

Next generation microarray bioinformatics : methods and protocols /
by: Wang, Junba, et al.
Published: (c201)

The Universal Optimism of the Self-Evidencing Mind
by: Elizabeth L. Fisher, et al.
Published: (2024-06-01)

Vodenje evidenc o procesu izobraževanja
by: Nataša Kegelj Kovačič
Published: (2003-12-01)

Evidenced-Based Claims About Evidence
by: David H. Howard PhD
Published: (2017-10-01)

Irish occupational therapists use of evidenced-based falls prevention programmes
by: Kim Lombard, et al.
Published: (2019-11-01)

Characterising and evidencing the effects of porosity in nano-electrochemistry
by: Batchelor-McAuley, C, et al.
Published: (2020)

Evidencing the outsourcing of social care provision in England
by: Bach-Mortensen, A, et al.
Published: (2024)

The provisional nature of science evidenced in times of pandemic
by: Carolina Sotério
Published: (2022-02-01)

Integration of bioinformatics and cellular experiments unveils the role of SYT12 in gastric cancer
by: Xingdong Niu, et al.
Published: (2024-10-01)

Next-Generation Sequencing and Bioinformatics Consortium Approach to Genomic Surveillance
by: Lindsay C. Morton, et al.
Published: (2024-10-01)

A Bioinformatics Toolkit for Next-Generation Sequencing in Clinical Oncology
by: Simon Cabello-Aguilar, et al.
Published: (2023-12-01)

Scalable Newborn Screening Solutions: Bioinformatics and Next-Generation Sequencing
by: Nicole Ruiz-Schultz, et al.
Published: (2021-09-01)

Next Generation Sequencing and Bioinformatics Analysis of Family Genetic Inheritance
by: Aquillah M. Kanzi, et al.
Published: (2020-10-01)

The non-sphericity of Triton's atmosphere as evidenced by stellar occultations
by: Person, Michael James
Published: (2010)

Survival of FDI : evidenced from Singapore outward investment.
by: Li, Amy Aisha., et al.
Published: (2008)