In Vitro Evaluation of a Solid Supersaturated Self Nanoemulsifying Drug Delivery System (Super-SNEDDS) of Aprepitant for Enhanced Solubility

In Vitro Evaluation of a Solid Supersaturated Self Nanoemulsifying Drug Delivery System (Super-SNEDDS) of Aprepitant for Enhanced Solubility

Aprepitant (APR) belongs to Class II of the Biopharmaceutical Classification System (BCS) because of its low aqueous solubility. The objective of the current work is to develop self-nanoemulsifying drug delivery systems (SNEDDS) of APR to enhance its aqueous solubility. Preformulation studies involv...

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Bibliographic Details
Main Authors:	Hakan Nazlı, Burcu Mesut, Yıldız Özsoy
Format:	Article
Language:	English
Published:	MDPI AG 2021-10-01
Series:	Pharmaceuticals
Subjects:	aprepitant supersaturated SNEDDS solid SNEDDS solubility enhancement soluplus<sup>®</sup> imwitor<sup>®</sup> 988
Online Access:	https://www.mdpi.com/1424-8247/14/11/1089

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