Replisome loading reduces chromatin motion independent of DNA synthesis

Replisome loading reduces chromatin motion independent of DNA synthesis

Chromatin has been shown to undergo diffusional motion, which is affected during gene transcription by RNA polymerase activity. However, the relationship between chromatin mobility and other genomic processes remains unclear. Hence, we set out to label the DNA directly in a sequence unbiased manner...

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Bibliographic Details
Main Authors: Maruthi Kumar Pabba, Christian Ritter, Vadim O Chagin, Janis Meyer, Kerem Celikay, Jeffrey H Stear, Dinah Loerke, Ksenia Kolobynina, Paulina Prorok, Alice Kristin Schmid, Heinrich Leonhardt, Karl Rohr, M Cristina Cardoso
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-10-01
Series:eLife
Subjects:
aphidicolin
cell cycle
chromatin tracking
diffusion
DNA replication
DNA labeling
Online Access:https://elifesciences.org/articles/87572

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