Incidence of type 2 diabetes mellitus and prediabetes in Kerala, India: results from a 10-year prospective cohort
Abstract Background Kerala, the southern state of India, has experienced sudden rise in the prevalence estimates of diabetes. A cohort study on the incidence of type 2 diabetes mellitus (T2DM) in Kerala state thus aptly bridges the lacuna of incidence estimate of T2DM from a population at risk. Meth...
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BMC
2019-01-01
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| Series: | BMC Public Health |
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| Online Access: | http://link.springer.com/article/10.1186/s12889-019-6445-6 |
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| author | Gadadharan Vijayakumar Sreeja Manghat Revathi Vijayakumar Leena Simon Liss Maria Scaria Aswathi Vijayakumar Ganapathy K. Sreehari V. Raman Kutty Arun Rachana Abdul Jaleel |
| author_facet | Gadadharan Vijayakumar Sreeja Manghat Revathi Vijayakumar Leena Simon Liss Maria Scaria Aswathi Vijayakumar Ganapathy K. Sreehari V. Raman Kutty Arun Rachana Abdul Jaleel |
| author_sort | Gadadharan Vijayakumar |
| collection | DOAJ |
| description | Abstract Background Kerala, the southern state of India, has experienced sudden rise in the prevalence estimates of diabetes. A cohort study on the incidence of type 2 diabetes mellitus (T2DM) in Kerala state thus aptly bridges the lacuna of incidence estimate of T2DM from a population at risk. Methods A 10-year prospective cohort study was carried out in two urban wards of central Kerala. The individuals who participated in the baseline survey in 2007 were again invited for a follow-up study in 2017. The data was analyzed using IBM SPSS Statistics for windows (version 21.0). Logistic regression analysis was used to estimate odds ratios and 95% confidence intervals. Findings are based on the 10-year follow-up data from 869 participants from the cohort. Results The overall follow-up and response rate of the study was 68.9 and 86.9% respectively. During the follow-up period, 190 people (21.9%) developed T2DM. The incidence rate of T2DM and impaired fasting glucose (IFG) were 24.5 per 1000 person years and 45.01 per 1000 person years respectively. Nearly 60% of participants with baseline IFG were converted to T2DM group in the follow-up period. Age > 45 years, family history of T2DM, BMI ≥ 25 kg/m2 and presence of central obesity emerged as important risk factors for incident T2DM. Conclusion High incidence of prediabetes over diabetes observed in this study shows an epidemic trend of T2DM in Kerala, India. It requires an immediate public health action. |
| first_indexed | 2024-12-13T02:37:58Z |
| format | Article |
| id | doaj.art-53743d8988b4483eaf38d97e6fa09229 |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-12-13T02:37:58Z |
| publishDate | 2019-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-53743d8988b4483eaf38d97e6fa092292022-12-22T00:02:21ZengBMCBMC Public Health1471-24582019-01-0119111010.1186/s12889-019-6445-6Incidence of type 2 diabetes mellitus and prediabetes in Kerala, India: results from a 10-year prospective cohortGadadharan Vijayakumar0Sreeja Manghat1Revathi Vijayakumar2Leena Simon3Liss Maria Scaria4Aswathi Vijayakumar5Ganapathy K. Sreehari6V. Raman Kutty7Arun Rachana8Abdul Jaleel9Medical Trust Hospital and Diabetes Care CentreMedical Trust Hospital and Diabetes Care CentreMedical Trust Hospital and Diabetes Care CentreMedical Trust Hospital and Diabetes Care CentreMedical Trust Hospital and Diabetes Care CentreMedical Trust Hospital and Diabetes Care CentreMedical Trust Hospital and Diabetes Care CentreAchutha Menon Centre, Sree Chitra Tirunal Institute for Medical Sciences and TechnologyChristian Medical CollegeRajiv Gandhi Centre for Biotechnology, Thycaud postAbstract Background Kerala, the southern state of India, has experienced sudden rise in the prevalence estimates of diabetes. A cohort study on the incidence of type 2 diabetes mellitus (T2DM) in Kerala state thus aptly bridges the lacuna of incidence estimate of T2DM from a population at risk. Methods A 10-year prospective cohort study was carried out in two urban wards of central Kerala. The individuals who participated in the baseline survey in 2007 were again invited for a follow-up study in 2017. The data was analyzed using IBM SPSS Statistics for windows (version 21.0). Logistic regression analysis was used to estimate odds ratios and 95% confidence intervals. Findings are based on the 10-year follow-up data from 869 participants from the cohort. Results The overall follow-up and response rate of the study was 68.9 and 86.9% respectively. During the follow-up period, 190 people (21.9%) developed T2DM. The incidence rate of T2DM and impaired fasting glucose (IFG) were 24.5 per 1000 person years and 45.01 per 1000 person years respectively. Nearly 60% of participants with baseline IFG were converted to T2DM group in the follow-up period. Age > 45 years, family history of T2DM, BMI ≥ 25 kg/m2 and presence of central obesity emerged as important risk factors for incident T2DM. Conclusion High incidence of prediabetes over diabetes observed in this study shows an epidemic trend of T2DM in Kerala, India. It requires an immediate public health action.http://link.springer.com/article/10.1186/s12889-019-6445-6Type 2 diabetesPrediabetesAsian IndiansIncidenceCohort |
| spellingShingle | Gadadharan Vijayakumar Sreeja Manghat Revathi Vijayakumar Leena Simon Liss Maria Scaria Aswathi Vijayakumar Ganapathy K. Sreehari V. Raman Kutty Arun Rachana Abdul Jaleel Incidence of type 2 diabetes mellitus and prediabetes in Kerala, India: results from a 10-year prospective cohort BMC Public Health Type 2 diabetes Prediabetes Asian Indians Incidence Cohort |
| title | Incidence of type 2 diabetes mellitus and prediabetes in Kerala, India: results from a 10-year prospective cohort |
| title_full | Incidence of type 2 diabetes mellitus and prediabetes in Kerala, India: results from a 10-year prospective cohort |
| title_fullStr | Incidence of type 2 diabetes mellitus and prediabetes in Kerala, India: results from a 10-year prospective cohort |
| title_full_unstemmed | Incidence of type 2 diabetes mellitus and prediabetes in Kerala, India: results from a 10-year prospective cohort |
| title_short | Incidence of type 2 diabetes mellitus and prediabetes in Kerala, India: results from a 10-year prospective cohort |
| title_sort | incidence of type 2 diabetes mellitus and prediabetes in kerala india results from a 10 year prospective cohort |
| topic | Type 2 diabetes Prediabetes Asian Indians Incidence Cohort |
| url | http://link.springer.com/article/10.1186/s12889-019-6445-6 |
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