A cortical biomarker of audibility and processing efficacy in children with single-sided deafness using a cochlear implant
Abstract The goals of the current study were to evaluate audibility and cortical speech processing, and to provide insight into binaural processing in children with single-sided deafness (CHwSSD) using a cochlear implant (CI). The P1 potential to acoustically-presented speech stimuli (/m/, /g/, /t/)...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-03-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-30399-0 |
| _version_ | 1797864622978498560 |
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| author | Y. Yaar-Soffer R. Kaplan-Neeman T. Greenbom S. Habiballah Y. Shapira Y. Henkin |
| author_facet | Y. Yaar-Soffer R. Kaplan-Neeman T. Greenbom S. Habiballah Y. Shapira Y. Henkin |
| author_sort | Y. Yaar-Soffer |
| collection | DOAJ |
| description | Abstract The goals of the current study were to evaluate audibility and cortical speech processing, and to provide insight into binaural processing in children with single-sided deafness (CHwSSD) using a cochlear implant (CI). The P1 potential to acoustically-presented speech stimuli (/m/, /g/, /t/) was recorded during monaural [Normal hearing (NH), CI], and bilateral (BIL, NH + CI) listening conditions within a clinical setting in 22 CHwSSD (mean age at CI/testing 4.7, 5.7 years). Robust P1 potentials were elicited in all children in the NH and BIL conditions. In the CI condition: (1) P1 prevalence was reduced yet was elicited in all but one child to at least one stimulus; (2) P1 latency was prolonged and amplitude was reduced, consequently leading to absence of binaural processing manifestations; (3) Correlation between P1 latency and age at CI/testing was weak and not significant; (4) P1 prevalence for /m/ was reduced and associated with CI manufacturer and duration of CI use. Results indicate that recording CAEPs to speech stimuli in clinical settings is feasible and valuable for the management of CHwSSD. While CAEPs provided evidence for effective audibility, a substantial mismatch in timing and synchrony of early-stage cortical processing between the CI and NH ear remains a barrier for the development of binaural interaction components. |
| first_indexed | 2024-04-09T22:56:02Z |
| format | Article |
| id | doaj.art-537c6413a5694b51991e25e8a5657b03 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-09T22:56:02Z |
| publishDate | 2023-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-537c6413a5694b51991e25e8a5657b032023-03-22T11:16:08ZengNature PortfolioScientific Reports2045-23222023-03-0113111110.1038/s41598-023-30399-0A cortical biomarker of audibility and processing efficacy in children with single-sided deafness using a cochlear implantY. Yaar-Soffer0R. Kaplan-Neeman1T. Greenbom2S. Habiballah3Y. Shapira4Y. Henkin5Hearing, Speech, and Language Center, Sheba Medical CenterHearing, Speech, and Language Center, Sheba Medical CenterHearing, Speech, and Language Center, Sheba Medical CenterDepartment of Communication Disorders, Haifa UniversityDepartment of Otolaryngology Head and Neck Surgery, Sheba Medical CenterHearing, Speech, and Language Center, Sheba Medical CenterAbstract The goals of the current study were to evaluate audibility and cortical speech processing, and to provide insight into binaural processing in children with single-sided deafness (CHwSSD) using a cochlear implant (CI). The P1 potential to acoustically-presented speech stimuli (/m/, /g/, /t/) was recorded during monaural [Normal hearing (NH), CI], and bilateral (BIL, NH + CI) listening conditions within a clinical setting in 22 CHwSSD (mean age at CI/testing 4.7, 5.7 years). Robust P1 potentials were elicited in all children in the NH and BIL conditions. In the CI condition: (1) P1 prevalence was reduced yet was elicited in all but one child to at least one stimulus; (2) P1 latency was prolonged and amplitude was reduced, consequently leading to absence of binaural processing manifestations; (3) Correlation between P1 latency and age at CI/testing was weak and not significant; (4) P1 prevalence for /m/ was reduced and associated with CI manufacturer and duration of CI use. Results indicate that recording CAEPs to speech stimuli in clinical settings is feasible and valuable for the management of CHwSSD. While CAEPs provided evidence for effective audibility, a substantial mismatch in timing and synchrony of early-stage cortical processing between the CI and NH ear remains a barrier for the development of binaural interaction components.https://doi.org/10.1038/s41598-023-30399-0 |
| spellingShingle | Y. Yaar-Soffer R. Kaplan-Neeman T. Greenbom S. Habiballah Y. Shapira Y. Henkin A cortical biomarker of audibility and processing efficacy in children with single-sided deafness using a cochlear implant Scientific Reports |
| title | A cortical biomarker of audibility and processing efficacy in children with single-sided deafness using a cochlear implant |
| title_full | A cortical biomarker of audibility and processing efficacy in children with single-sided deafness using a cochlear implant |
| title_fullStr | A cortical biomarker of audibility and processing efficacy in children with single-sided deafness using a cochlear implant |
| title_full_unstemmed | A cortical biomarker of audibility and processing efficacy in children with single-sided deafness using a cochlear implant |
| title_short | A cortical biomarker of audibility and processing efficacy in children with single-sided deafness using a cochlear implant |
| title_sort | cortical biomarker of audibility and processing efficacy in children with single sided deafness using a cochlear implant |
| url | https://doi.org/10.1038/s41598-023-30399-0 |
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