Single Functionalized pRNA/Gold Nanoparticle for Ultrasensitive MicroRNA Detection Using Electrochemical Surface‐Enhanced Raman Spectroscopy

Single Functionalized pRNA/Gold Nanoparticle for Ultrasensitive MicroRNA Detection Using Electrochemical Surface‐Enhanced Raman Spectroscopy

Abstract Controlling the selective one‐to‐one conjugation of RNA with nanoparticles is vital for future applications of RNA nanotechnology. Here, the monofunctionalization of a gold nanoparticle (AuNP) with a single copy of RNA is developed for ultrasensitive microRNA‐155 quantification using electr...

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Bibliographic Details
Main Authors: Taek Lee, Mohsen Mohammadniaei, Hui Zhang, Jinho Yoon, Hye Kyu Choi, Sijin Guo, Peixuan Guo, Jeong‐Woo Choi
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Advanced Science
Subjects:
biosensors
electrochemical surface‐enhanced Raman spectroscopy (EC‐SERS)
microRNAs
monofunctionalization
pRNA 3WJ
Online Access:https://doi.org/10.1002/advs.201902477

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