"N-factor/Anergic Margin" of resistance / susceptibility to hanseniasis. II. The general acceptance of the theory

In this second article of a series about the pathogenetical theory "N-factor/Anergic Margin" of hanseniasis, the first sympathethic editorial reactions (1938-1940) and the general acceptance of the theory (1943-1977) are reviewed. Acceptance under modified terminology ("potential imm...

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Bibliographic Details
Main Author: Abrahão ROTBERG
Format: Article
Language:English
Published: Instituto Lauro de Souza Lima 1977-11-01
Series:Hansenologia Internationalis
Subjects:
Online Access:https://periodicos.saude.sp.gov.br/hansenologia/article/view/36064
Description
Summary:In this second article of a series about the pathogenetical theory "N-factor/Anergic Margin" of hanseniasis, the first sympathethic editorial reactions (1938-1940) and the general acceptance of the theory (1943-1977) are reviewed. Acceptance under modified terminology ("potential immunity", `inherited ability to destroy bacteria or form granuloma", etc. — for the N-factor"; "defect of cell-mediated immunity", "constitutional inaptitude to react", etc., for the "Anergic Margin"), will be reviewed in the third article of the series, together with the author's rebuttals to criticisms.
ISSN:1982-5161