Recent advancements in nanomaterial-laden contact lenses for diagnosis and treatment of glaucoma, review and update
Abstract Despite the existence of numerous eye drops in the market, most of them are not sufficiently effective because of quick clearance and the barriers within the eye. To increase the delivery of the drugs to the eye, various new formulations have been explored in recent decades. These formulati...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-11-01
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| Series: | Journal of Nanobiotechnology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12951-023-02166-w |
| _version_ | 1827770369775239168 |
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| author | Roghayyeh Baghban Mohammad Reza Talebnejad Aidin Meshksar Mojtaba Heydari Mohammad Reza Khalili |
| author_facet | Roghayyeh Baghban Mohammad Reza Talebnejad Aidin Meshksar Mojtaba Heydari Mohammad Reza Khalili |
| author_sort | Roghayyeh Baghban |
| collection | DOAJ |
| description | Abstract Despite the existence of numerous eye drops in the market, most of them are not sufficiently effective because of quick clearance and the barriers within the eye. To increase the delivery of the drugs to the eye, various new formulations have been explored in recent decades. These formulations aim to enhance drug retention and penetration, while enabling sustained drug release over extended periods. One such innovative approach is the utilization of contact lenses, which were originally designed for cosmetic purposes and vision correction. Contact lenses have appeared as a promising formulation for ocular drug delivery, as they can increase the bioavailability of drugs in the eye and diminish unwanted side effects. They are specifically appropriate for treating chronic eye conditions, making them an area of interest for researchers in the field of ophthalmology. This review outlines the promising potential of nanomaterial-laden contact lenses for diagnosis and treatment of glaucoma. It classifies therapeutic approaches based on nanomaterial type, summarizes diagnostic advances, discusses improvement of contact lenses properties, covers marketing perspectives, and acknowledges the challenges of these innovative contact lenses for glaucoma management. |
| first_indexed | 2024-03-11T12:38:37Z |
| format | Article |
| id | doaj.art-5386c5173b2b4139bf18a9ad7d8fba83 |
| institution | Directory Open Access Journal |
| issn | 1477-3155 |
| language | English |
| last_indexed | 2024-03-11T12:38:37Z |
| publishDate | 2023-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Nanobiotechnology |
| spelling | doaj.art-5386c5173b2b4139bf18a9ad7d8fba832023-11-05T12:28:43ZengBMCJournal of Nanobiotechnology1477-31552023-11-0121112210.1186/s12951-023-02166-wRecent advancements in nanomaterial-laden contact lenses for diagnosis and treatment of glaucoma, review and updateRoghayyeh Baghban0Mohammad Reza Talebnejad1Aidin Meshksar2Mojtaba Heydari3Mohammad Reza Khalili4Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical SciencesPoostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical SciencesPoostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical SciencesPoostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical SciencesPoostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical SciencesAbstract Despite the existence of numerous eye drops in the market, most of them are not sufficiently effective because of quick clearance and the barriers within the eye. To increase the delivery of the drugs to the eye, various new formulations have been explored in recent decades. These formulations aim to enhance drug retention and penetration, while enabling sustained drug release over extended periods. One such innovative approach is the utilization of contact lenses, which were originally designed for cosmetic purposes and vision correction. Contact lenses have appeared as a promising formulation for ocular drug delivery, as they can increase the bioavailability of drugs in the eye and diminish unwanted side effects. They are specifically appropriate for treating chronic eye conditions, making them an area of interest for researchers in the field of ophthalmology. This review outlines the promising potential of nanomaterial-laden contact lenses for diagnosis and treatment of glaucoma. It classifies therapeutic approaches based on nanomaterial type, summarizes diagnostic advances, discusses improvement of contact lenses properties, covers marketing perspectives, and acknowledges the challenges of these innovative contact lenses for glaucoma management.https://doi.org/10.1186/s12951-023-02166-wGlaucomaContact lensesDrug delivery systemDiagnosisTreatment |
| spellingShingle | Roghayyeh Baghban Mohammad Reza Talebnejad Aidin Meshksar Mojtaba Heydari Mohammad Reza Khalili Recent advancements in nanomaterial-laden contact lenses for diagnosis and treatment of glaucoma, review and update Journal of Nanobiotechnology Glaucoma Contact lenses Drug delivery system Diagnosis Treatment |
| title | Recent advancements in nanomaterial-laden contact lenses for diagnosis and treatment of glaucoma, review and update |
| title_full | Recent advancements in nanomaterial-laden contact lenses for diagnosis and treatment of glaucoma, review and update |
| title_fullStr | Recent advancements in nanomaterial-laden contact lenses for diagnosis and treatment of glaucoma, review and update |
| title_full_unstemmed | Recent advancements in nanomaterial-laden contact lenses for diagnosis and treatment of glaucoma, review and update |
| title_short | Recent advancements in nanomaterial-laden contact lenses for diagnosis and treatment of glaucoma, review and update |
| title_sort | recent advancements in nanomaterial laden contact lenses for diagnosis and treatment of glaucoma review and update |
| topic | Glaucoma Contact lenses Drug delivery system Diagnosis Treatment |
| url | https://doi.org/10.1186/s12951-023-02166-w |
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