Physical Training Chronically Stimulates the Motor Neuron Cell Nucleus in the Ts65Dn Mouse, a Model of Down Syndrome

Physical Training Chronically Stimulates the Motor Neuron Cell Nucleus in the Ts65Dn Mouse, a Model of Down Syndrome

Down syndrome (DS) is a genetically-based disease based on the trisomy of chromosome 21 (Hsa21). DS is characterized by intellectual disability in association with several pathological traits among which early aging and altered motor coordination are prominent. Physical training or passive exercise...

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Bibliographic Details
Main Authors: Chiara Rita Inguscio, Maria Assunta Lacavalla, Barbara Cisterna, Carlo Zancanaro, Manuela Malatesta
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cells
Subjects:
cell nucleus
Down syndrome
motor neuron
physical exercise
transmission electron microscopy
Ts65Dn mouse
Online Access:https://www.mdpi.com/2073-4409/12/11/1488

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