Unusual presentation of acquired thrombotic thrombocytopenic purpura (TTP) versus catastrophic antiphospholipid syndrome in a patient with Moya‐Moya disease, case report, and literature review
Key Clinical Message Coincidences in medicine are not so common. We are presenting a case of a patient diagnosed with Moya‐Moya disease and antiphospholipid syndrome (APS) who presented with clinical and laboratory characteristics of catastrophic APS versus TTP. The diagnosis was a challenge because...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-05-01
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| Series: | Clinical Case Reports |
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| Online Access: | https://doi.org/10.1002/ccr3.7317 |
| _version_ | 1797820434224250880 |
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| author | Nehemias Guevara‐Rodriguez Gabriela Marmanillo‐Mendoza Jorge Castelar Camelia Ciobanu Ilmana Fulger |
| author_facet | Nehemias Guevara‐Rodriguez Gabriela Marmanillo‐Mendoza Jorge Castelar Camelia Ciobanu Ilmana Fulger |
| author_sort | Nehemias Guevara‐Rodriguez |
| collection | DOAJ |
| description | Key Clinical Message Coincidences in medicine are not so common. We are presenting a case of a patient diagnosed with Moya‐Moya disease and antiphospholipid syndrome (APS) who presented with clinical and laboratory characteristics of catastrophic APS versus TTP. The diagnosis was a challenge because characteristics were overlapping. Nevertheless, a decision to treat the patient for TTP was made with afterward improvement. MMD has been associated with multiple immune disorders; however, only one case of acquired thrombotic thrombocytopenic purpura has been documented in association with this disease. None has been associated with catastrophic antiphospholipid syndrome. We are presenting a challenging case where all these three medical conditions were present at the same time. |
| first_indexed | 2024-03-13T09:38:18Z |
| format | Article |
| id | doaj.art-53891683949b4e12b4cbea38d54e1838 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-03-13T09:38:18Z |
| publishDate | 2023-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-53891683949b4e12b4cbea38d54e18382023-05-25T05:58:40ZengWileyClinical Case Reports2050-09042023-05-01115n/an/a10.1002/ccr3.7317Unusual presentation of acquired thrombotic thrombocytopenic purpura (TTP) versus catastrophic antiphospholipid syndrome in a patient with Moya‐Moya disease, case report, and literature reviewNehemias Guevara‐Rodriguez0Gabriela Marmanillo‐Mendoza1Jorge Castelar2Camelia Ciobanu3Ilmana Fulger4Department of Medicine, Internal Medicine St. Barnabas Hospital Health System The Bronx New York USADepartment of Medicine, Internal Medicine St. Barnabas Hospital Health System The Bronx New York USADepartment of Medicine, Internal Medicine St. Barnabas Hospital Health System The Bronx New York USADepartment of Medicine, Internal Medicine St. Barnabas Hospital Health System The Bronx New York USADepartment of Medicine, Internal Medicine, Department of Hemato‐Oncology St. Barnabas Hospital Health System The Bronx New York USAKey Clinical Message Coincidences in medicine are not so common. We are presenting a case of a patient diagnosed with Moya‐Moya disease and antiphospholipid syndrome (APS) who presented with clinical and laboratory characteristics of catastrophic APS versus TTP. The diagnosis was a challenge because characteristics were overlapping. Nevertheless, a decision to treat the patient for TTP was made with afterward improvement. MMD has been associated with multiple immune disorders; however, only one case of acquired thrombotic thrombocytopenic purpura has been documented in association with this disease. None has been associated with catastrophic antiphospholipid syndrome. We are presenting a challenging case where all these three medical conditions were present at the same time.https://doi.org/10.1002/ccr3.7317antiphospholipid syndrome (APS)Moya‐Moya diseaseMoya‐Moya syndromethrombotic thrombocytopenic purpura (TTP)treatment |
| spellingShingle | Nehemias Guevara‐Rodriguez Gabriela Marmanillo‐Mendoza Jorge Castelar Camelia Ciobanu Ilmana Fulger Unusual presentation of acquired thrombotic thrombocytopenic purpura (TTP) versus catastrophic antiphospholipid syndrome in a patient with Moya‐Moya disease, case report, and literature review Clinical Case Reports antiphospholipid syndrome (APS) Moya‐Moya disease Moya‐Moya syndrome thrombotic thrombocytopenic purpura (TTP) treatment |
| title | Unusual presentation of acquired thrombotic thrombocytopenic purpura (TTP) versus catastrophic antiphospholipid syndrome in a patient with Moya‐Moya disease, case report, and literature review |
| title_full | Unusual presentation of acquired thrombotic thrombocytopenic purpura (TTP) versus catastrophic antiphospholipid syndrome in a patient with Moya‐Moya disease, case report, and literature review |
| title_fullStr | Unusual presentation of acquired thrombotic thrombocytopenic purpura (TTP) versus catastrophic antiphospholipid syndrome in a patient with Moya‐Moya disease, case report, and literature review |
| title_full_unstemmed | Unusual presentation of acquired thrombotic thrombocytopenic purpura (TTP) versus catastrophic antiphospholipid syndrome in a patient with Moya‐Moya disease, case report, and literature review |
| title_short | Unusual presentation of acquired thrombotic thrombocytopenic purpura (TTP) versus catastrophic antiphospholipid syndrome in a patient with Moya‐Moya disease, case report, and literature review |
| title_sort | unusual presentation of acquired thrombotic thrombocytopenic purpura ttp versus catastrophic antiphospholipid syndrome in a patient with moya moya disease case report and literature review |
| topic | antiphospholipid syndrome (APS) Moya‐Moya disease Moya‐Moya syndrome thrombotic thrombocytopenic purpura (TTP) treatment |
| url | https://doi.org/10.1002/ccr3.7317 |
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