Intercellular crosstalk shapes purinergic metabolism and signaling in cancer cells

Intercellular crosstalk shapes purinergic metabolism and signaling in cancer cells

Summary: CD73-derived adenosine suppresses anti-cancer immunity, and CD73 inhibitors are currently evaluated in several clinical trials. Here, we have assessed enzyme kinetics of all key purinergic ectoenzymes in five cancer cell lines (Hodgkin lymphoma, multiple myeloma, pancreas adenocarcinoma, ur...

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Bibliographic Details
Main Authors:	Julia Hesse, Bodo Steckel, Peter Dieterich, Siyar Aydin, Andreas Deussen, Jürgen Schrader
Format:	Article
Language:	English
Published:	Elsevier 2024-01-01
Series:	Cell Reports
Subjects:	CP: Cancer
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124723016546

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