HuD promotes BDNF expression in brain neurons via selective stabilization of the BDNF long 3'UTR mRNA.

HuD promotes BDNF expression in brain neurons via selective stabilization of the BDNF long 3'UTR mRNA.

Complex regulation of brain-derived neurotrophic factor (BDNF) governs its intricate functions in brain development and neuronal plasticity. Besides tight transcriptional control from multiple distinct promoters, alternative 3'end processing of the BDNF transcripts generates either a long or a...

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Bibliographic Details
Main Authors: Megan Allen, Clark Bird, Wei Feng, Guanglu Liu, Wenqi Li, Nora I Perrone-Bizzozero, Yue Feng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3561324?pdf=render

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