A Ferroptosis-Related Gene Prognostic Index to Predict Temozolomide Sensitivity and Immune Checkpoint Inhibitor Response for Glioma

A Ferroptosis-Related Gene Prognostic Index to Predict Temozolomide Sensitivity and Immune Checkpoint Inhibitor Response for Glioma

Background: Gliomas are highly lethal brain tumors. Despite multimodality therapy with surgery, radiotherapy, chemotherapy, and immunotherapy, glioma prognosis remains poor. Ferroptosis is a crucial tumor suppressor mechanism that has been proven to be effective in anticancer therapy. However, the i...

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Bibliographic Details
Main Authors: Yonghua Cai, Xianqiu Liang, Zhengming Zhan, Yu Zeng, Jie Lin, Anqi Xu, Shuaishuai Xue, Wei Xu, Peng Chai, Yangqi Mao, Zibin Song, Lei Han, Jianqi Xiao, Ye Song, Xian Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ferroptosis
glioma
temozolomide
immune checkpoint inhibitor
tumor microenvironment
ferroptosis-based anticancer therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.812422/full

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