Combining Metabolic Engineering and Multiplexed Screening Methods for 3-Hydroxypropionic Acid Production in Pichia pastoris
Production of 3-hydroxypropionic acid (3-HP) in Pichia pastoris (syn. Komagataella phaffii) via the malonyl-CoA pathway has been recently demonstrated using glycerol as a carbon source, but the reported metrics were not commercially relevant. The flux through the heterologous pathway from malonyl-Co...
Auteurs principaux: | , , , |
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Format: | Article |
Langue: | English |
Publié: |
Frontiers Media S.A.
2022-07-01
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Collection: | Frontiers in Bioengineering and Biotechnology |
Sujets: | |
Accès en ligne: | https://www.frontiersin.org/articles/10.3389/fbioe.2022.942304/full |