Non-glycosylated G protein with CpG ODN provides robust protection against respiratory syncytial virus without inducing eosinophilia

Non-glycosylated G protein with CpG ODN provides robust protection against respiratory syncytial virus without inducing eosinophilia

IntroductionRespiratory syncytial virus (RSV) vaccines targeting the fusion glycoprotein (F protein) are highly effective clinically in preventing RSV challenges. The attachment glycoprotein (G protein) is a potentially effective vaccine antigen candidate, as it is important for cell adhesion during...

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Bibliographic Details
Main Authors: Eigo Kawahara, Takehiko Shibata, Toshiro Hirai, Yasuo Yoshioka
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
adjuvant
CpG oligodeoxynucleotide
eosinophil
G protein
respiratory syncytial virus
vaccine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1282016/full

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