Current Advances in the Biosynthesis, Metabolism, and Transcriptional Regulation of α-Tomatine in Tomato
Steroid glycoalkaloids (SGAs) are a class of cholesterol-derived metabolites commonly found in the <i>Solanaceae</i> plants. α-Tomatine, a well-known bitter-tasting compound, is the major SGA in tomato, accumulating extensively in all plant tissues, particularly in the leaves and immatur...
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| Format: | Article |
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MDPI AG
2023-09-01
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| Series: | Plants |
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| Online Access: | https://www.mdpi.com/2223-7747/12/18/3289 |
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| author | Yuanyuan Liu Hanru Hu Rujia Yang Zhujun Zhu Kejun Cheng |
| author_facet | Yuanyuan Liu Hanru Hu Rujia Yang Zhujun Zhu Kejun Cheng |
| author_sort | Yuanyuan Liu |
| collection | DOAJ |
| description | Steroid glycoalkaloids (SGAs) are a class of cholesterol-derived metabolites commonly found in the <i>Solanaceae</i> plants. α-Tomatine, a well-known bitter-tasting compound, is the major SGA in tomato, accumulating extensively in all plant tissues, particularly in the leaves and immature green fruits. α-Tomatine exhibits diverse biological activities that contribute to plant defense against pathogens and herbivores, as well as conferring certain medicinal benefits for human health. This review summarizes the current knowledge on α-tomatine, including its molecular chemical structure, physical and chemical properties, biosynthetic and metabolic pathways, and transcriptional regulatory mechanisms. Moreover, potential future research directions and applications of α-tomatine are also discussed. |
| first_indexed | 2024-03-10T22:13:14Z |
| format | Article |
| id | doaj.art-5393db03e96947c99632fb1da3c98910 |
| institution | Directory Open Access Journal |
| issn | 2223-7747 |
| language | English |
| last_indexed | 2024-03-10T22:13:14Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj.art-5393db03e96947c99632fb1da3c989102023-11-19T12:32:46ZengMDPI AGPlants2223-77472023-09-011218328910.3390/plants12183289Current Advances in the Biosynthesis, Metabolism, and Transcriptional Regulation of α-Tomatine in TomatoYuanyuan Liu0Hanru Hu1Rujia Yang2Zhujun Zhu3Kejun Cheng4Collaborative Innovation Center for Efficient and Green Production of Agriculture in Mountainous Areas of Zhejiang Province, Key Laboratory of Quality and Safety Control for Subtropical Fruit and Vegetable, Ministry of Agriculture and Rural Affairs, College of Horticulture Science, Zhejiang A&F University, Hangzhou 311300, ChinaCollaborative Innovation Center for Efficient and Green Production of Agriculture in Mountainous Areas of Zhejiang Province, Key Laboratory of Quality and Safety Control for Subtropical Fruit and Vegetable, Ministry of Agriculture and Rural Affairs, College of Horticulture Science, Zhejiang A&F University, Hangzhou 311300, ChinaCollaborative Innovation Center for Efficient and Green Production of Agriculture in Mountainous Areas of Zhejiang Province, Key Laboratory of Quality and Safety Control for Subtropical Fruit and Vegetable, Ministry of Agriculture and Rural Affairs, College of Horticulture Science, Zhejiang A&F University, Hangzhou 311300, ChinaCollaborative Innovation Center for Efficient and Green Production of Agriculture in Mountainous Areas of Zhejiang Province, Key Laboratory of Quality and Safety Control for Subtropical Fruit and Vegetable, Ministry of Agriculture and Rural Affairs, College of Horticulture Science, Zhejiang A&F University, Hangzhou 311300, ChinaChemical Biology Center, Lishui Institute of Agriculture and Forestry Sciences, Lishui 323000, ChinaSteroid glycoalkaloids (SGAs) are a class of cholesterol-derived metabolites commonly found in the <i>Solanaceae</i> plants. α-Tomatine, a well-known bitter-tasting compound, is the major SGA in tomato, accumulating extensively in all plant tissues, particularly in the leaves and immature green fruits. α-Tomatine exhibits diverse biological activities that contribute to plant defense against pathogens and herbivores, as well as conferring certain medicinal benefits for human health. This review summarizes the current knowledge on α-tomatine, including its molecular chemical structure, physical and chemical properties, biosynthetic and metabolic pathways, and transcriptional regulatory mechanisms. Moreover, potential future research directions and applications of α-tomatine are also discussed.https://www.mdpi.com/2223-7747/12/18/3289tomatoα-tomatinebiosynthesismetabolismtranscriptional regulationbiological activity |
| spellingShingle | Yuanyuan Liu Hanru Hu Rujia Yang Zhujun Zhu Kejun Cheng Current Advances in the Biosynthesis, Metabolism, and Transcriptional Regulation of α-Tomatine in Tomato Plants tomato α-tomatine biosynthesis metabolism transcriptional regulation biological activity |
| title | Current Advances in the Biosynthesis, Metabolism, and Transcriptional Regulation of α-Tomatine in Tomato |
| title_full | Current Advances in the Biosynthesis, Metabolism, and Transcriptional Regulation of α-Tomatine in Tomato |
| title_fullStr | Current Advances in the Biosynthesis, Metabolism, and Transcriptional Regulation of α-Tomatine in Tomato |
| title_full_unstemmed | Current Advances in the Biosynthesis, Metabolism, and Transcriptional Regulation of α-Tomatine in Tomato |
| title_short | Current Advances in the Biosynthesis, Metabolism, and Transcriptional Regulation of α-Tomatine in Tomato |
| title_sort | current advances in the biosynthesis metabolism and transcriptional regulation of α tomatine in tomato |
| topic | tomato α-tomatine biosynthesis metabolism transcriptional regulation biological activity |
| url | https://www.mdpi.com/2223-7747/12/18/3289 |
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