Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus"
Abstract The Hydrocephalus Association (HA) workshop, Driving Common Pathways: Extending Insights from Posthemorrhagic Hydrocephalus, was held on November 4 and 5, 2019 at Washington University in St. Louis. The workshop brought together a diverse group of basic, translational, and clinical scientis...
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Format: | Article |
Language: | English |
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BMC
2023-01-01
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Series: | Fluids and Barriers of the CNS |
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Online Access: | https://doi.org/10.1186/s12987-023-00406-7 |
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author | Jason K. Karimy Jessie C. Newville Cameron Sadegh Jill A. Morris Edwin S. Monuki David D. Limbrick James P. McAllister II Jenna E. Koschnitzky Maria K. Lehtinen Lauren L. Jantzie |
author_facet | Jason K. Karimy Jessie C. Newville Cameron Sadegh Jill A. Morris Edwin S. Monuki David D. Limbrick James P. McAllister II Jenna E. Koschnitzky Maria K. Lehtinen Lauren L. Jantzie |
author_sort | Jason K. Karimy |
collection | DOAJ |
description | Abstract The Hydrocephalus Association (HA) workshop, Driving Common Pathways: Extending Insights from Posthemorrhagic Hydrocephalus, was held on November 4 and 5, 2019 at Washington University in St. Louis. The workshop brought together a diverse group of basic, translational, and clinical scientists conducting research on multiple hydrocephalus etiologies with select outside researchers. The main goals of the workshop were to explore areas of potential overlap between hydrocephalus etiologies and identify drug targets that could positively impact various forms of hydrocephalus. This report details the major themes of the workshop and the research presented on three cell types that are targets for new hydrocephalus interventions: choroid plexus epithelial cells, ventricular ependymal cells, and immune cells (macrophages and microglia). |
first_indexed | 2024-04-10T22:45:53Z |
format | Article |
id | doaj.art-539642b289504d639e5e88ca53cd606e |
institution | Directory Open Access Journal |
issn | 2045-8118 |
language | English |
last_indexed | 2024-04-10T22:45:53Z |
publishDate | 2023-01-01 |
publisher | BMC |
record_format | Article |
series | Fluids and Barriers of the CNS |
spelling | doaj.art-539642b289504d639e5e88ca53cd606e2023-01-15T12:19:06ZengBMCFluids and Barriers of the CNS2045-81182023-01-0120111710.1186/s12987-023-00406-7Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus"Jason K. Karimy0Jessie C. Newville1Cameron Sadegh2Jill A. Morris3Edwin S. Monuki4David D. Limbrick5James P. McAllister II6Jenna E. Koschnitzky7Maria K. Lehtinen8Lauren L. Jantzie9Department of Family Medicine, Mountain Area Health Education Center - BooneDepartment of Pediatrics and Neurosurgery, Johns Hopkins Children’s Center, Johns Hopkins School of MedicineDepartment of Neurosurgery, Massachusetts General Hospital and Harvard Medical SchoolNational Institute of Neurological Disorders and Stroke, Neuroscience Center, National Institutes of HealthDepartments of Pathology & Laboratory Medicine and Developmental & Cell Biology, University of California IrvineDepartments of Neurosurgery and Pediatrics, Washington University School of Medicine in St. LouisDepartments of Neurosurgery and Pediatrics, Washington University School of Medicine in St. LouisHydrocephalus AssociationDepartment of Pathology, Boston Children’s HospitalDepartment of Pediatrics and Neurosurgery, Johns Hopkins Children’s Center, Johns Hopkins School of MedicineAbstract The Hydrocephalus Association (HA) workshop, Driving Common Pathways: Extending Insights from Posthemorrhagic Hydrocephalus, was held on November 4 and 5, 2019 at Washington University in St. Louis. The workshop brought together a diverse group of basic, translational, and clinical scientists conducting research on multiple hydrocephalus etiologies with select outside researchers. The main goals of the workshop were to explore areas of potential overlap between hydrocephalus etiologies and identify drug targets that could positively impact various forms of hydrocephalus. This report details the major themes of the workshop and the research presented on three cell types that are targets for new hydrocephalus interventions: choroid plexus epithelial cells, ventricular ependymal cells, and immune cells (macrophages and microglia).https://doi.org/10.1186/s12987-023-00406-7HydrocephalusPosthemorrhagicPost-infectiousIntraventricular hemorrhageGerminal matrix hemorrhageCilia |
spellingShingle | Jason K. Karimy Jessie C. Newville Cameron Sadegh Jill A. Morris Edwin S. Monuki David D. Limbrick James P. McAllister II Jenna E. Koschnitzky Maria K. Lehtinen Lauren L. Jantzie Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus" Fluids and Barriers of the CNS Hydrocephalus Posthemorrhagic Post-infectious Intraventricular hemorrhage Germinal matrix hemorrhage Cilia |
title | Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus" |
title_full | Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus" |
title_fullStr | Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus" |
title_full_unstemmed | Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus" |
title_short | Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus" |
title_sort | outcomes of the 2019 hydrocephalus association workshop driving common pathways extending insights from posthemorrhagic hydrocephalus |
topic | Hydrocephalus Posthemorrhagic Post-infectious Intraventricular hemorrhage Germinal matrix hemorrhage Cilia |
url | https://doi.org/10.1186/s12987-023-00406-7 |
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