Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus"

Abstract The Hydrocephalus Association (HA) workshop, Driving Common Pathways: Extending Insights from Posthemorrhagic Hydrocephalus, was held on November 4 and 5, 2019 at Washington University in St. Louis. The workshop brought together a diverse group of basic, translational, and clinical scientis...

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Main Authors: Jason K. Karimy, Jessie C. Newville, Cameron Sadegh, Jill A. Morris, Edwin S. Monuki, David D. Limbrick, James P. McAllister II, Jenna E. Koschnitzky, Maria K. Lehtinen, Lauren L. Jantzie
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:https://doi.org/10.1186/s12987-023-00406-7
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author Jason K. Karimy
Jessie C. Newville
Cameron Sadegh
Jill A. Morris
Edwin S. Monuki
David D. Limbrick
James P. McAllister II
Jenna E. Koschnitzky
Maria K. Lehtinen
Lauren L. Jantzie
author_facet Jason K. Karimy
Jessie C. Newville
Cameron Sadegh
Jill A. Morris
Edwin S. Monuki
David D. Limbrick
James P. McAllister II
Jenna E. Koschnitzky
Maria K. Lehtinen
Lauren L. Jantzie
author_sort Jason K. Karimy
collection DOAJ
description Abstract The Hydrocephalus Association (HA) workshop, Driving Common Pathways: Extending Insights from Posthemorrhagic Hydrocephalus, was held on November 4 and 5, 2019 at Washington University in St. Louis. The workshop brought together a diverse group of basic, translational, and clinical scientists conducting research on multiple hydrocephalus etiologies with select outside researchers. The main goals of the workshop were to explore areas of potential overlap between hydrocephalus etiologies and identify drug targets that could positively impact various forms of hydrocephalus. This report details the major themes of the workshop and the research presented on three cell types that are targets for new hydrocephalus interventions: choroid plexus epithelial cells, ventricular ependymal cells, and immune cells (macrophages and microglia).
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spelling doaj.art-539642b289504d639e5e88ca53cd606e2023-01-15T12:19:06ZengBMCFluids and Barriers of the CNS2045-81182023-01-0120111710.1186/s12987-023-00406-7Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus"Jason K. Karimy0Jessie C. Newville1Cameron Sadegh2Jill A. Morris3Edwin S. Monuki4David D. Limbrick5James P. McAllister II6Jenna E. Koschnitzky7Maria K. Lehtinen8Lauren L. Jantzie9Department of Family Medicine, Mountain Area Health Education Center - BooneDepartment of Pediatrics and Neurosurgery, Johns Hopkins Children’s Center, Johns Hopkins School of MedicineDepartment of Neurosurgery, Massachusetts General Hospital and Harvard Medical SchoolNational Institute of Neurological Disorders and Stroke, Neuroscience Center, National Institutes of HealthDepartments of Pathology & Laboratory Medicine and Developmental & Cell Biology, University of California IrvineDepartments of Neurosurgery and Pediatrics, Washington University School of Medicine in St. LouisDepartments of Neurosurgery and Pediatrics, Washington University School of Medicine in St. LouisHydrocephalus AssociationDepartment of Pathology, Boston Children’s HospitalDepartment of Pediatrics and Neurosurgery, Johns Hopkins Children’s Center, Johns Hopkins School of MedicineAbstract The Hydrocephalus Association (HA) workshop, Driving Common Pathways: Extending Insights from Posthemorrhagic Hydrocephalus, was held on November 4 and 5, 2019 at Washington University in St. Louis. The workshop brought together a diverse group of basic, translational, and clinical scientists conducting research on multiple hydrocephalus etiologies with select outside researchers. The main goals of the workshop were to explore areas of potential overlap between hydrocephalus etiologies and identify drug targets that could positively impact various forms of hydrocephalus. This report details the major themes of the workshop and the research presented on three cell types that are targets for new hydrocephalus interventions: choroid plexus epithelial cells, ventricular ependymal cells, and immune cells (macrophages and microglia).https://doi.org/10.1186/s12987-023-00406-7HydrocephalusPosthemorrhagicPost-infectiousIntraventricular hemorrhageGerminal matrix hemorrhageCilia
spellingShingle Jason K. Karimy
Jessie C. Newville
Cameron Sadegh
Jill A. Morris
Edwin S. Monuki
David D. Limbrick
James P. McAllister II
Jenna E. Koschnitzky
Maria K. Lehtinen
Lauren L. Jantzie
Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus"
Fluids and Barriers of the CNS
Hydrocephalus
Posthemorrhagic
Post-infectious
Intraventricular hemorrhage
Germinal matrix hemorrhage
Cilia
title Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus"
title_full Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus"
title_fullStr Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus"
title_full_unstemmed Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus"
title_short Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus"
title_sort outcomes of the 2019 hydrocephalus association workshop driving common pathways extending insights from posthemorrhagic hydrocephalus
topic Hydrocephalus
Posthemorrhagic
Post-infectious
Intraventricular hemorrhage
Germinal matrix hemorrhage
Cilia
url https://doi.org/10.1186/s12987-023-00406-7
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