GLP-1 localisation and proglucagon gene expression in healthy and diabetic mouse ileum
Glucagon-like peptide-1 (GLP-1) is a polypeptide that is mainly produced by intestinal L cells and is encoded by the proglucagon gene. In this study, GLP-1 localisation was investigated in the ileum of healthy and diabetic mice by immunohistochemistry and proglucagon gene expression was assayed by r...
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Format: | Article |
Language: | English |
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Sciendo
2018-07-01
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Series: | Journal of Veterinary Research |
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Online Access: | https://doi.org/10.2478/jvetres-2018-0033 |
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author | Taşçı Serap Koral Bingöl Seyit Ali |
author_facet | Taşçı Serap Koral Bingöl Seyit Ali |
author_sort | Taşçı Serap Koral |
collection | DOAJ |
description | Glucagon-like peptide-1 (GLP-1) is a polypeptide that is mainly produced by intestinal L cells and is encoded by the proglucagon gene. In this study, GLP-1 localisation was investigated in the ileum of healthy and diabetic mice by immunohistochemistry and proglucagon gene expression was assayed by reverse transcription-polymerase chain reaction. |
first_indexed | 2024-12-16T11:08:31Z |
format | Article |
id | doaj.art-5396b02ad88148708a0a913600e73234 |
institution | Directory Open Access Journal |
issn | 2450-8608 |
language | English |
last_indexed | 2024-12-16T11:08:31Z |
publishDate | 2018-07-01 |
publisher | Sciendo |
record_format | Article |
series | Journal of Veterinary Research |
spelling | doaj.art-5396b02ad88148708a0a913600e732342022-12-21T22:33:48ZengSciendoJournal of Veterinary Research2450-86082018-07-0162223724210.2478/jvetres-2018-0033jvetres-2018-0033GLP-1 localisation and proglucagon gene expression in healthy and diabetic mouse ileumTaşçı Serap Koral0Bingöl Seyit Ali1Department of Histology and Embryology, Faculty of Veterinary Medicine, Kafkas University, 36100Kars, TurkeyDepartment of Histology and Embryology, Faculty of Medicine, Kafkas University, 36100Kars, TurkeyGlucagon-like peptide-1 (GLP-1) is a polypeptide that is mainly produced by intestinal L cells and is encoded by the proglucagon gene. In this study, GLP-1 localisation was investigated in the ileum of healthy and diabetic mice by immunohistochemistry and proglucagon gene expression was assayed by reverse transcription-polymerase chain reaction.https://doi.org/10.2478/jvetres-2018-0033micediabetes mellitusglp-1l cellsproglucagon |
spellingShingle | Taşçı Serap Koral Bingöl Seyit Ali GLP-1 localisation and proglucagon gene expression in healthy and diabetic mouse ileum Journal of Veterinary Research mice diabetes mellitus glp-1 l cells proglucagon |
title | GLP-1 localisation and proglucagon gene expression in healthy and diabetic mouse ileum |
title_full | GLP-1 localisation and proglucagon gene expression in healthy and diabetic mouse ileum |
title_fullStr | GLP-1 localisation and proglucagon gene expression in healthy and diabetic mouse ileum |
title_full_unstemmed | GLP-1 localisation and proglucagon gene expression in healthy and diabetic mouse ileum |
title_short | GLP-1 localisation and proglucagon gene expression in healthy and diabetic mouse ileum |
title_sort | glp 1 localisation and proglucagon gene expression in healthy and diabetic mouse ileum |
topic | mice diabetes mellitus glp-1 l cells proglucagon |
url | https://doi.org/10.2478/jvetres-2018-0033 |
work_keys_str_mv | AT tascıserapkoral glp1localisationandproglucagongeneexpressioninhealthyanddiabeticmouseileum AT bingolseyitali glp1localisationandproglucagongeneexpressioninhealthyanddiabeticmouseileum |