GLP-1 localisation and proglucagon gene expression in healthy and diabetic mouse ileum

Glucagon-like peptide-1 (GLP-1) is a polypeptide that is mainly produced by intestinal L cells and is encoded by the proglucagon gene. In this study, GLP-1 localisation was investigated in the ileum of healthy and diabetic mice by immunohistochemistry and proglucagon gene expression was assayed by r...

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Main Authors: Taşçı Serap Koral, Bingöl Seyit Ali
Format: Article
Language:English
Published: Sciendo 2018-07-01
Series:Journal of Veterinary Research
Subjects:
Online Access:https://doi.org/10.2478/jvetres-2018-0033
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author Taşçı Serap Koral
Bingöl Seyit Ali
author_facet Taşçı Serap Koral
Bingöl Seyit Ali
author_sort Taşçı Serap Koral
collection DOAJ
description Glucagon-like peptide-1 (GLP-1) is a polypeptide that is mainly produced by intestinal L cells and is encoded by the proglucagon gene. In this study, GLP-1 localisation was investigated in the ileum of healthy and diabetic mice by immunohistochemistry and proglucagon gene expression was assayed by reverse transcription-polymerase chain reaction.
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spelling doaj.art-5396b02ad88148708a0a913600e732342022-12-21T22:33:48ZengSciendoJournal of Veterinary Research2450-86082018-07-0162223724210.2478/jvetres-2018-0033jvetres-2018-0033GLP-1 localisation and proglucagon gene expression in healthy and diabetic mouse ileumTaşçı Serap Koral0Bingöl Seyit Ali1Department of Histology and Embryology, Faculty of Veterinary Medicine, Kafkas University, 36100Kars, TurkeyDepartment of Histology and Embryology, Faculty of Medicine, Kafkas University, 36100Kars, TurkeyGlucagon-like peptide-1 (GLP-1) is a polypeptide that is mainly produced by intestinal L cells and is encoded by the proglucagon gene. In this study, GLP-1 localisation was investigated in the ileum of healthy and diabetic mice by immunohistochemistry and proglucagon gene expression was assayed by reverse transcription-polymerase chain reaction.https://doi.org/10.2478/jvetres-2018-0033micediabetes mellitusglp-1l cellsproglucagon
spellingShingle Taşçı Serap Koral
Bingöl Seyit Ali
GLP-1 localisation and proglucagon gene expression in healthy and diabetic mouse ileum
Journal of Veterinary Research
mice
diabetes mellitus
glp-1
l cells
proglucagon
title GLP-1 localisation and proglucagon gene expression in healthy and diabetic mouse ileum
title_full GLP-1 localisation and proglucagon gene expression in healthy and diabetic mouse ileum
title_fullStr GLP-1 localisation and proglucagon gene expression in healthy and diabetic mouse ileum
title_full_unstemmed GLP-1 localisation and proglucagon gene expression in healthy and diabetic mouse ileum
title_short GLP-1 localisation and proglucagon gene expression in healthy and diabetic mouse ileum
title_sort glp 1 localisation and proglucagon gene expression in healthy and diabetic mouse ileum
topic mice
diabetes mellitus
glp-1
l cells
proglucagon
url https://doi.org/10.2478/jvetres-2018-0033
work_keys_str_mv AT tascıserapkoral glp1localisationandproglucagongeneexpressioninhealthyanddiabeticmouseileum
AT bingolseyitali glp1localisationandproglucagongeneexpressioninhealthyanddiabeticmouseileum