High-Risk Neuroblastoma: A Surgical Perspective
High-risk neuroblastoma requires multimodal treatment including systemic chemotherapy, surgical resection, radiation therapy, stem cell transplant, and immunotherapy. Surgeons play a vital role in obtaining local control of neuroblastoma and must therefore be knowledgeable about this complex patholo...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-02-01
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| Series: | Children |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9067/10/2/388 |
| _version_ | 1797621639167344640 |
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| author | Jillian C. Jacobson Rachael A. Clark Dai H. Chung |
| author_facet | Jillian C. Jacobson Rachael A. Clark Dai H. Chung |
| author_sort | Jillian C. Jacobson |
| collection | DOAJ |
| description | High-risk neuroblastoma requires multimodal treatment including systemic chemotherapy, surgical resection, radiation therapy, stem cell transplant, and immunotherapy. Surgeons play a vital role in obtaining local control of neuroblastoma and must therefore be knowledgeable about this complex pathology. This article provides a review of the optimal timing and extent of resection, the impact of various image-defined risk factors on surgical planning, and surgical approaches and techniques to enhance the resection of tumors in different anatomic locations. |
| first_indexed | 2024-03-11T08:59:53Z |
| format | Article |
| id | doaj.art-5397e0cd88584f548da6d290b17d0bef |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-11T08:59:53Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-5397e0cd88584f548da6d290b17d0bef2023-11-16T19:50:05ZengMDPI AGChildren2227-90672023-02-0110238810.3390/children10020388High-Risk Neuroblastoma: A Surgical PerspectiveJillian C. Jacobson0Rachael A. Clark1Dai H. Chung2Department of Pediatric Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Pediatric Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390, USADepartment of Pediatric Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390, USAHigh-risk neuroblastoma requires multimodal treatment including systemic chemotherapy, surgical resection, radiation therapy, stem cell transplant, and immunotherapy. Surgeons play a vital role in obtaining local control of neuroblastoma and must therefore be knowledgeable about this complex pathology. This article provides a review of the optimal timing and extent of resection, the impact of various image-defined risk factors on surgical planning, and surgical approaches and techniques to enhance the resection of tumors in different anatomic locations.https://www.mdpi.com/2227-9067/10/2/388neuroblastomahigh-riskpediatric surgical oncologysurgical resection |
| spellingShingle | Jillian C. Jacobson Rachael A. Clark Dai H. Chung High-Risk Neuroblastoma: A Surgical Perspective Children neuroblastoma high-risk pediatric surgical oncology surgical resection |
| title | High-Risk Neuroblastoma: A Surgical Perspective |
| title_full | High-Risk Neuroblastoma: A Surgical Perspective |
| title_fullStr | High-Risk Neuroblastoma: A Surgical Perspective |
| title_full_unstemmed | High-Risk Neuroblastoma: A Surgical Perspective |
| title_short | High-Risk Neuroblastoma: A Surgical Perspective |
| title_sort | high risk neuroblastoma a surgical perspective |
| topic | neuroblastoma high-risk pediatric surgical oncology surgical resection |
| url | https://www.mdpi.com/2227-9067/10/2/388 |
| work_keys_str_mv | AT jilliancjacobson highriskneuroblastomaasurgicalperspective AT rachaelaclark highriskneuroblastomaasurgicalperspective AT daihchung highriskneuroblastomaasurgicalperspective |