Thromboprophylaxis for Hospitalized Patients with Inflammatory Bowel Disease—Are We There Yet?
Patients with inflammatory bowel disease (IBD) have a high risk of venous thromboembolism (VTE) events in both hospitalized patients and outpatients. Although thromboprophylaxis is recommended for hospitalized patients with IBD, implementation is not universal, especially for non IBD-related hospita...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-08-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/9/9/2753 |
| _version_ | 1797555521888190464 |
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| author | Asaf Levartovsky Yiftach Barash Shomron Ben-Horin Bella Ungar Eyal Klang Shelly Soffer Uri Kopylov |
| author_facet | Asaf Levartovsky Yiftach Barash Shomron Ben-Horin Bella Ungar Eyal Klang Shelly Soffer Uri Kopylov |
| author_sort | Asaf Levartovsky |
| collection | DOAJ |
| description | Patients with inflammatory bowel disease (IBD) have a high risk of venous thromboembolism (VTE) events in both hospitalized patients and outpatients. Although thromboprophylaxis is recommended for hospitalized patients with IBD, implementation is not universal, especially for non IBD-related hospitalizations. Our objective was to present VTE and thromboprophylaxis adherence rates among hospitalized patients with IBD. An electronic data repository was created of all patients with IBD who visited the emergency department (ED) of our tertiary medical center between 2012 and 2018. The data included tabular variables and free-text physician records. We searched the data for VTE events, using ICD10 coding. Overall, there were 7009 ED visits of 2405 patients with IBD, 1556 (64.7%) with Crohn’s disease (CD) and 849 (35.3%) with ulcerative colitis (UC). Thromboprophylaxis was administered in 463 hospitalizations (12.4% of IBD-related and 10.9% of non IBD-related hospitalizations, <i>p</i> = 0.13). Nineteen VTEs were diagnosed in the ED and seventeen were diagnosed during hospitalization (11 non IBD-related and 6 IBD-related hospitalizations, 0.6% and 0.28% respectively, <i>p</i> = 0.12). One patient died during hospitalization and an additional two in the 90 days post-discharge from hospitalization (unrelated to VTEs). In conclusion, thromboprophylaxis rates in hospitalized patients with IBD are low, despite possible implications and established guidelines. Thromboprophylaxis should be implemented in patients with IBD hospitalized for all indications. |
| first_indexed | 2024-03-10T16:48:42Z |
| format | Article |
| id | doaj.art-5397ef8cc107412c885f3ff3a7f1bbff |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T16:48:42Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-5397ef8cc107412c885f3ff3a7f1bbff2023-11-20T11:22:12ZengMDPI AGJournal of Clinical Medicine2077-03832020-08-0199275310.3390/jcm9092753Thromboprophylaxis for Hospitalized Patients with Inflammatory Bowel Disease—Are We There Yet?Asaf Levartovsky0Yiftach Barash1Shomron Ben-Horin2Bella Ungar3Eyal Klang4Shelly Soffer5Uri Kopylov6Department of Gastroenterology, Sheba Medical Center, Tel Hashomer, Ramat Gan 5262100, IsraelSackler Faculty of Medicine, Tel Aviv University, Ramat Aviv 69978, Tel Aviv, IsraelDepartment of Gastroenterology, Sheba Medical Center, Tel Hashomer, Ramat Gan 5262100, IsraelDepartment of Gastroenterology, Sheba Medical Center, Tel Hashomer, Ramat Gan 5262100, IsraelSackler Faculty of Medicine, Tel Aviv University, Ramat Aviv 69978, Tel Aviv, IsraelSackler Faculty of Medicine, Tel Aviv University, Ramat Aviv 69978, Tel Aviv, IsraelDepartment of Gastroenterology, Sheba Medical Center, Tel Hashomer, Ramat Gan 5262100, IsraelPatients with inflammatory bowel disease (IBD) have a high risk of venous thromboembolism (VTE) events in both hospitalized patients and outpatients. Although thromboprophylaxis is recommended for hospitalized patients with IBD, implementation is not universal, especially for non IBD-related hospitalizations. Our objective was to present VTE and thromboprophylaxis adherence rates among hospitalized patients with IBD. An electronic data repository was created of all patients with IBD who visited the emergency department (ED) of our tertiary medical center between 2012 and 2018. The data included tabular variables and free-text physician records. We searched the data for VTE events, using ICD10 coding. Overall, there were 7009 ED visits of 2405 patients with IBD, 1556 (64.7%) with Crohn’s disease (CD) and 849 (35.3%) with ulcerative colitis (UC). Thromboprophylaxis was administered in 463 hospitalizations (12.4% of IBD-related and 10.9% of non IBD-related hospitalizations, <i>p</i> = 0.13). Nineteen VTEs were diagnosed in the ED and seventeen were diagnosed during hospitalization (11 non IBD-related and 6 IBD-related hospitalizations, 0.6% and 0.28% respectively, <i>p</i> = 0.12). One patient died during hospitalization and an additional two in the 90 days post-discharge from hospitalization (unrelated to VTEs). In conclusion, thromboprophylaxis rates in hospitalized patients with IBD are low, despite possible implications and established guidelines. Thromboprophylaxis should be implemented in patients with IBD hospitalized for all indications.https://www.mdpi.com/2077-0383/9/9/2753venous thromboembolismprophylaxisinflammatory bowel diseasesextra-intestinal manifestationshospitalization |
| spellingShingle | Asaf Levartovsky Yiftach Barash Shomron Ben-Horin Bella Ungar Eyal Klang Shelly Soffer Uri Kopylov Thromboprophylaxis for Hospitalized Patients with Inflammatory Bowel Disease—Are We There Yet? Journal of Clinical Medicine venous thromboembolism prophylaxis inflammatory bowel diseases extra-intestinal manifestations hospitalization |
| title | Thromboprophylaxis for Hospitalized Patients with Inflammatory Bowel Disease—Are We There Yet? |
| title_full | Thromboprophylaxis for Hospitalized Patients with Inflammatory Bowel Disease—Are We There Yet? |
| title_fullStr | Thromboprophylaxis for Hospitalized Patients with Inflammatory Bowel Disease—Are We There Yet? |
| title_full_unstemmed | Thromboprophylaxis for Hospitalized Patients with Inflammatory Bowel Disease—Are We There Yet? |
| title_short | Thromboprophylaxis for Hospitalized Patients with Inflammatory Bowel Disease—Are We There Yet? |
| title_sort | thromboprophylaxis for hospitalized patients with inflammatory bowel disease are we there yet |
| topic | venous thromboembolism prophylaxis inflammatory bowel diseases extra-intestinal manifestations hospitalization |
| url | https://www.mdpi.com/2077-0383/9/9/2753 |
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