Preparation of an Active Dressing by In Situ Biosynthesis of a Bacterial Cellulose–Graphene Oxide Composite
This paper presents a simple method of obtaining a bacterial cellulose (BC) composite with the addition of graphene oxide (GO) using an in situ method and studies the influence of GO nanoparticles on the structure and properties of the obtained membranes. Microorganisms obtained from Golden Deliciou...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/14/14/2864 |
| _version_ | 1797433177668583424 |
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| author | Tobiasz Gabryś Beata Fryczkowska Janusz Fabia Dorota Biniaś |
| author_facet | Tobiasz Gabryś Beata Fryczkowska Janusz Fabia Dorota Biniaś |
| author_sort | Tobiasz Gabryś |
| collection | DOAJ |
| description | This paper presents a simple method of obtaining a bacterial cellulose (BC) composite with the addition of graphene oxide (GO) using an in situ method and studies the influence of GO nanoparticles on the structure and properties of the obtained membranes. Microorganisms obtained from Golden Delicious apple vinegar were used to obtain the BC. During the biosynthesis, GO was introduced in the amounts of 3.7, 5.4 and 7.1% <i>w</i>/<i>w</i>. The resulting BC/GO composite was characterized by high water content (~400%), a thickness of about 1.1 mm (in wet form) and a cellulose nanofiber diameter of ~100 nm. The possibility of using the resulting composite membranes as potential active dressings with the sustained-release analgesic medicine—paracetamol—was investigated. The BC/GO composite membranes were characterized by a medicine sorption of 60 mg/g of BC, a slow desorption time, a constant medicine concentration over time and an 80% paracetamol release rate after 24 h. The morphology of membrane surfaces and cross-sections were examined by means of scanning electron microscopy (SEM). Infrared spectroscopy (FTIR), X-ray structure studies (WAXS) as well as thermal analysis (TGA) demonstrated the presence of GO in the BC matrix and interactions between the matrix and the additive. |
| first_indexed | 2024-03-09T10:12:26Z |
| format | Article |
| id | doaj.art-5399759ee980414ea0deec97c3e3d841 |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-09T10:12:26Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-5399759ee980414ea0deec97c3e3d8412023-12-01T22:36:41ZengMDPI AGPolymers2073-43602022-07-011414286410.3390/polym14142864Preparation of an Active Dressing by In Situ Biosynthesis of a Bacterial Cellulose–Graphene Oxide CompositeTobiasz Gabryś0Beata Fryczkowska1Janusz Fabia2Dorota Biniaś3Department of Material Science, Faculty of Materials, Civil and Environmental Engineering, University of Bielsko-Biala, Willowa 2, 43-309 Bielsko-Biala, PolandDepartment of Environmental Protection and Engineering, Faculty of Materials, Civil and Environmental Engineering, University of Bielsko-Biala, Willowa 2, 43-309 Bielsko-Biala, PolandDepartment of Material Science, Faculty of Materials, Civil and Environmental Engineering, University of Bielsko-Biala, Willowa 2, 43-309 Bielsko-Biala, PolandDepartment of Environmental Protection and Engineering, Faculty of Materials, Civil and Environmental Engineering, University of Bielsko-Biala, Willowa 2, 43-309 Bielsko-Biala, PolandThis paper presents a simple method of obtaining a bacterial cellulose (BC) composite with the addition of graphene oxide (GO) using an in situ method and studies the influence of GO nanoparticles on the structure and properties of the obtained membranes. Microorganisms obtained from Golden Delicious apple vinegar were used to obtain the BC. During the biosynthesis, GO was introduced in the amounts of 3.7, 5.4 and 7.1% <i>w</i>/<i>w</i>. The resulting BC/GO composite was characterized by high water content (~400%), a thickness of about 1.1 mm (in wet form) and a cellulose nanofiber diameter of ~100 nm. The possibility of using the resulting composite membranes as potential active dressings with the sustained-release analgesic medicine—paracetamol—was investigated. The BC/GO composite membranes were characterized by a medicine sorption of 60 mg/g of BC, a slow desorption time, a constant medicine concentration over time and an 80% paracetamol release rate after 24 h. The morphology of membrane surfaces and cross-sections were examined by means of scanning electron microscopy (SEM). Infrared spectroscopy (FTIR), X-ray structure studies (WAXS) as well as thermal analysis (TGA) demonstrated the presence of GO in the BC matrix and interactions between the matrix and the additive.https://www.mdpi.com/2073-4360/14/14/2864bacterial cellulosegraphene oxidebiosynthesiscomposite membranesnanofibers |
| spellingShingle | Tobiasz Gabryś Beata Fryczkowska Janusz Fabia Dorota Biniaś Preparation of an Active Dressing by In Situ Biosynthesis of a Bacterial Cellulose–Graphene Oxide Composite Polymers bacterial cellulose graphene oxide biosynthesis composite membranes nanofibers |
| title | Preparation of an Active Dressing by In Situ Biosynthesis of a Bacterial Cellulose–Graphene Oxide Composite |
| title_full | Preparation of an Active Dressing by In Situ Biosynthesis of a Bacterial Cellulose–Graphene Oxide Composite |
| title_fullStr | Preparation of an Active Dressing by In Situ Biosynthesis of a Bacterial Cellulose–Graphene Oxide Composite |
| title_full_unstemmed | Preparation of an Active Dressing by In Situ Biosynthesis of a Bacterial Cellulose–Graphene Oxide Composite |
| title_short | Preparation of an Active Dressing by In Situ Biosynthesis of a Bacterial Cellulose–Graphene Oxide Composite |
| title_sort | preparation of an active dressing by in situ biosynthesis of a bacterial cellulose graphene oxide composite |
| topic | bacterial cellulose graphene oxide biosynthesis composite membranes nanofibers |
| url | https://www.mdpi.com/2073-4360/14/14/2864 |
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