H3K4me3 Histone ChIP-Seq Analysis Reveals Molecular Mechanisms Responsible for Neutrophil Dysfunction in HIV-Infected Individuals

H3K4me3 Histone ChIP-Seq Analysis Reveals Molecular Mechanisms Responsible for Neutrophil Dysfunction in HIV-Infected Individuals

Peripheral neutrophils in HIV-infected individuals are characterized by impairment of chemotaxis, phagocytosis, bactericidal activity, and oxidative burst ability regardless of whether patients are receiving antiretroviral therapy or not. Neutrophil dysfunction leads not only to increased susceptibi...

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Bibliographic Details
Main Authors: Paweł Piatek, Maciej Tarkowski, Magdalena Namiecinska, Agostino Riva, Marek Wieczorek, Sylwia Michlewska, Justyna Dulska, Małgorzata Domowicz, Małgorzata Kulińska-Michalska, Natalia Lewkowicz, Przemysław Lewkowicz
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
neutrophils
human immunodeficiency virus
H3K4me3
ChIPSeq
innate immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.682094/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.682094/full

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