Monochorionic twins discordant for trisomy 13: A case report, systematic literature search and synthesis of available evidence
Abstract This article presents the tenth reported case of monochorionic twins discordant for trisomy 13. Discordant aneuploidies in monochorionic twins are rare. Aetiologies include mitotic error in early cell division and “rescue” chromosome loss in an initially trisomic zygote. Clinicians should o...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-12-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.3244 |
| _version_ | 1818597221077090304 |
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| author | Emily F. Cornish Ruwan Wimalasundera George Attilakos |
| author_facet | Emily F. Cornish Ruwan Wimalasundera George Attilakos |
| author_sort | Emily F. Cornish |
| collection | DOAJ |
| description | Abstract This article presents the tenth reported case of monochorionic twins discordant for trisomy 13. Discordant aneuploidies in monochorionic twins are rare. Aetiologies include mitotic error in early cell division and “rescue” chromosome loss in an initially trisomic zygote. Clinicians should offer early amniocentesis of both sacs and consider selective termination. |
| first_indexed | 2024-12-16T11:44:21Z |
| format | Article |
| id | doaj.art-539d798474364e3784b6d62a912bd6a1 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-12-16T11:44:21Z |
| publishDate | 2020-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-539d798474364e3784b6d62a912bd6a12022-12-21T22:32:51ZengWileyClinical Case Reports2050-09042020-12-018122797280110.1002/ccr3.3244Monochorionic twins discordant for trisomy 13: A case report, systematic literature search and synthesis of available evidenceEmily F. Cornish0Ruwan Wimalasundera1George Attilakos2UCL Elizabeth Garrett Anderson Institute for Women’s Health University College London (UCL) London UKFetal Medicine Unit University College London Hospitals London UKFetal Medicine Unit University College London Hospitals London UKAbstract This article presents the tenth reported case of monochorionic twins discordant for trisomy 13. Discordant aneuploidies in monochorionic twins are rare. Aetiologies include mitotic error in early cell division and “rescue” chromosome loss in an initially trisomic zygote. Clinicians should offer early amniocentesis of both sacs and consider selective termination.https://doi.org/10.1002/ccr3.3244amniocentesisdiscordant anomaliesmonochorionic twinsselective terminationtrisomy 13 |
| spellingShingle | Emily F. Cornish Ruwan Wimalasundera George Attilakos Monochorionic twins discordant for trisomy 13: A case report, systematic literature search and synthesis of available evidence Clinical Case Reports amniocentesis discordant anomalies monochorionic twins selective termination trisomy 13 |
| title | Monochorionic twins discordant for trisomy 13: A case report, systematic literature search and synthesis of available evidence |
| title_full | Monochorionic twins discordant for trisomy 13: A case report, systematic literature search and synthesis of available evidence |
| title_fullStr | Monochorionic twins discordant for trisomy 13: A case report, systematic literature search and synthesis of available evidence |
| title_full_unstemmed | Monochorionic twins discordant for trisomy 13: A case report, systematic literature search and synthesis of available evidence |
| title_short | Monochorionic twins discordant for trisomy 13: A case report, systematic literature search and synthesis of available evidence |
| title_sort | monochorionic twins discordant for trisomy 13 a case report systematic literature search and synthesis of available evidence |
| topic | amniocentesis discordant anomalies monochorionic twins selective termination trisomy 13 |
| url | https://doi.org/10.1002/ccr3.3244 |
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