Comparison of subdermal and perforator delay techniques on a rat flap model
Background: In this study, we investigated the subdermal and perforator delay phenomena as a method to improve flap survival. Materials and Methods: In this experimental study, we used 24 rats in three groups. In the control group, the dorsal flaps were elevated and reinserted back to their place. I...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Thieme Medical Publishers, Inc.
2018-05-01
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| Series: | Indian Journal of Plastic Surgery |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/ijps.IJPS_28_17 |
| _version_ | 1819006156667879424 |
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| author | Dincer Altinel Burcu Biltekin Merdan Serin Ugur Sahin Muzaffer Altindas |
| author_facet | Dincer Altinel Burcu Biltekin Merdan Serin Ugur Sahin Muzaffer Altindas |
| author_sort | Dincer Altinel |
| collection | DOAJ |
| description | Background: In this study, we investigated the subdermal and perforator delay phenomena as a method to improve flap survival. Materials and Methods: In this experimental study, we used 24 rats in three groups. In the control group, the dorsal flaps were elevated and reinserted back to their place. In the experimental groups, we practiced the delay phenomena with two different techniques. In the first experimental group, cranial and lateral side incisions were performed; however, the flaps were not cut-off from the underlying fascia. In the second experimental group, we placed a silicon sheet under the planned flap to cut-off the circulation from the perforator vessels. Four weeks after the delay procedure, the flaps were raised completely and reinserted back to their place. Results: The average of necrotic area in the control group was 21.9% (±7.70). There was no necrosis in both experimental groups (P < 0.0001). Histological examination revealed that collagen density in both of the experimental groups was increased in comparison to the control group, it has only been found a significant first experimental group (P = 0.0315). We have not found any significant difference in lymphocyte density between the groups. Angiographic imaging has showed an increase in the vascular density in the flaps of the first experimental group. Conclusion: We believe that both of these delay techniques can be adapted to clinical applications and used safely to increase flap survival. |
| first_indexed | 2024-12-21T00:04:12Z |
| format | Article |
| id | doaj.art-539def7d74d44eb5bdd2006d451a8d72 |
| institution | Directory Open Access Journal |
| issn | 0970-0358 1998-376X |
| language | English |
| last_indexed | 2024-12-21T00:04:12Z |
| publishDate | 2018-05-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | Indian Journal of Plastic Surgery |
| spelling | doaj.art-539def7d74d44eb5bdd2006d451a8d722022-12-21T19:22:32ZengThieme Medical Publishers, Inc.Indian Journal of Plastic Surgery0970-03581998-376X2018-05-01510219620110.4103/ijps.IJPS_28_17Comparison of subdermal and perforator delay techniques on a rat flap modelDincer Altinel0Burcu Biltekin1Merdan Serin2Ugur Sahin3Muzaffer Altindas4Department of Plastic and Reconstructive Surgery, Istanbul Training and Research Hospital, Istanbul, TurkeyDepartment of Histology and Embryology, Istanbul University Cerrahpasa Medical School, Istanbul, TurkeyDepartment of Plastic and Reconstructive Surgery, Istanbul Training and Research Hospital, Istanbul, TurkeyDepartment of Plastic and Reconstructive Surgery, Bahcelievler Medicana Hospital, Istanbul, TurkeyDepartment of Plastic and Reconstructive Surgery, Istanbul Diabetes Hospital, Istanbul, TurkeyBackground: In this study, we investigated the subdermal and perforator delay phenomena as a method to improve flap survival. Materials and Methods: In this experimental study, we used 24 rats in three groups. In the control group, the dorsal flaps were elevated and reinserted back to their place. In the experimental groups, we practiced the delay phenomena with two different techniques. In the first experimental group, cranial and lateral side incisions were performed; however, the flaps were not cut-off from the underlying fascia. In the second experimental group, we placed a silicon sheet under the planned flap to cut-off the circulation from the perforator vessels. Four weeks after the delay procedure, the flaps were raised completely and reinserted back to their place. Results: The average of necrotic area in the control group was 21.9% (±7.70). There was no necrosis in both experimental groups (P < 0.0001). Histological examination revealed that collagen density in both of the experimental groups was increased in comparison to the control group, it has only been found a significant first experimental group (P = 0.0315). We have not found any significant difference in lymphocyte density between the groups. Angiographic imaging has showed an increase in the vascular density in the flaps of the first experimental group. Conclusion: We believe that both of these delay techniques can be adapted to clinical applications and used safely to increase flap survival.http://www.thieme-connect.de/DOI/DOI?10.4103/ijps.IJPS_28_17flap delayratskin flap |
| spellingShingle | Dincer Altinel Burcu Biltekin Merdan Serin Ugur Sahin Muzaffer Altindas Comparison of subdermal and perforator delay techniques on a rat flap model Indian Journal of Plastic Surgery flap delay rat skin flap |
| title | Comparison of subdermal and perforator delay techniques on a rat flap model |
| title_full | Comparison of subdermal and perforator delay techniques on a rat flap model |
| title_fullStr | Comparison of subdermal and perforator delay techniques on a rat flap model |
| title_full_unstemmed | Comparison of subdermal and perforator delay techniques on a rat flap model |
| title_short | Comparison of subdermal and perforator delay techniques on a rat flap model |
| title_sort | comparison of subdermal and perforator delay techniques on a rat flap model |
| topic | flap delay rat skin flap |
| url | http://www.thieme-connect.de/DOI/DOI?10.4103/ijps.IJPS_28_17 |
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