ASK1-P38 Pathway is Important for Anoikis Induced by Microtubule-Targeting Aryl Chloroethylureas
PURPOSE. We investigated the involvement of MAPK signaling in the cell death mechanisms of classical microtubule interfering agents (MIA) and aryl-3-(2-chloroethyl)ureas (CEU) acting as antimitotics, along with CEU that don’t affect directly microtubules (non-MIA CEU). METHODS. To ascertain the act...
Main Authors: | Jessica S Fortin, Alexandre Patenaude, Rena G Deschesnes, Marie-France Côté, Eric Petitclerc, René C.-Gaudreault |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2010-06-01
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Series: | Journal of Pharmacy & Pharmaceutical Sciences |
Online Access: | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/7306 |
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