Prevalence of atrial fibrillation and the risk of cardiovascular mortality among hypertensive elderly population in northeast China

Abstract Little is known about the epidemiology and impact of atrial fibrillation (AF) on cardiovascular diseases (CVD) mortality among hypertensive elderly population in northeast China. The community‐based study included 4497 hypertensive elderly residents aged ≥65 years who lived in northeast Chi...

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Main Authors: Zhenwei Xia, Wei Dang, Xue Yang, Qun Sun, Jixu Sun, Lei Shi, Shize Sun, Le An, Xiaojing Li, Hongbo Peng, Shuang Liu, Ling Yue, Hongyun Chen
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:The Journal of Clinical Hypertension
Subjects:
Online Access:https://doi.org/10.1111/jch.14483
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author Zhenwei Xia
Wei Dang
Xue Yang
Qun Sun
Jixu Sun
Lei Shi
Shize Sun
Le An
Xiaojing Li
Hongbo Peng
Shuang Liu
Ling Yue
Hongyun Chen
author_facet Zhenwei Xia
Wei Dang
Xue Yang
Qun Sun
Jixu Sun
Lei Shi
Shize Sun
Le An
Xiaojing Li
Hongbo Peng
Shuang Liu
Ling Yue
Hongyun Chen
author_sort Zhenwei Xia
collection DOAJ
description Abstract Little is known about the epidemiology and impact of atrial fibrillation (AF) on cardiovascular diseases (CVD) mortality among hypertensive elderly population in northeast China. The community‐based study included 4497 hypertensive elderly residents aged ≥65 years who lived in northeast China from September 2017 to March 2019. Information on CVD deaths was obtained from baseline until July 31, 2021. Cox proportional hazard regression models were performed in the evaluation of CVD mortality. We identified 101 persons with AF. The prevalence of AF was 2.2% among elderly hypertensive population, which increased significantly with age. The prevalence of AF was higher in men than in women. The awareness rate was 51.5%, higher in urban areas than in rural areas (68.8% vs 43.5%, P = .018). Only 4.0% patients received oral anticoagulant (OAC) therapy among AF patients. Moreover, diabetes (26.7%) and dyslipidemia (37.6%) were highly prevalent in AF patients. Furthermore, 212 persons died due to CVD (14.7/1000 person‐years) during a median follow‐up of 3.2 years. AF patients had a 3.42 (95% CI: 2.07‐5.63) times higher risk of CVD mortality than the patients without AF in the fully adjusted model. Therefore, the burden of AF among hypertensive elderly population in northeast China was considerable. Long‐term screening and management strategies for AF and related risk factors are required among hypertensive elderly in northeast China.
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spelling doaj.art-53a3d441937949d9b84d1fd1ec80be332023-10-30T13:26:49ZengWileyThe Journal of Clinical Hypertension1524-61751751-71762022-05-0124563063710.1111/jch.14483Prevalence of atrial fibrillation and the risk of cardiovascular mortality among hypertensive elderly population in northeast ChinaZhenwei Xia0Wei Dang1Xue Yang2Qun Sun3Jixu Sun4Lei Shi5Shize Sun6Le An7Xiaojing Li8Hongbo Peng9Shuang Liu10Ling Yue11Hongyun Chen12Department of Cardiology Dalian Municipal Central Hospital Dalian Liaoning ChinaDepartment of Cardiology Dalian Municipal Central Hospital Dalian Liaoning ChinaDepartment of Cardiology Dalian Municipal Central Hospital Dalian Liaoning ChinaDepartment of Chronic Disease Disease Control and Prevention of Chaoyang City Chaoyang Liaoning ChinaDepartment of Chronic Disease Disease Control and Prevention of Dandong City Dandong Liaoning ChinaDepartment of Chronic Disease Disease Control and Prevention of Liaoyang City Liaoyang Liaoning ChinaDepartment of Cardiology Dalian Municipal Central Hospital Dalian Liaoning ChinaDepartment of Cardiology Dalian Municipal Central Hospital Dalian Liaoning ChinaDepartment of Cardiology Dalian Municipal Central Hospital Dalian Liaoning ChinaDepartment of Cardiology Dalian Municipal Central Hospital Dalian Liaoning ChinaDepartment of Ultrasound The Fourth Hospital of China Medical University Shenyang Liaoning ChinaDepartment of Ultrasound The Fourth Hospital of China Medical University Shenyang Liaoning ChinaDepartment of Cardiology Dalian Municipal Central Hospital Dalian Liaoning ChinaAbstract Little is known about the epidemiology and impact of atrial fibrillation (AF) on cardiovascular diseases (CVD) mortality among hypertensive elderly population in northeast China. The community‐based study included 4497 hypertensive elderly residents aged ≥65 years who lived in northeast China from September 2017 to March 2019. Information on CVD deaths was obtained from baseline until July 31, 2021. Cox proportional hazard regression models were performed in the evaluation of CVD mortality. We identified 101 persons with AF. The prevalence of AF was 2.2% among elderly hypertensive population, which increased significantly with age. The prevalence of AF was higher in men than in women. The awareness rate was 51.5%, higher in urban areas than in rural areas (68.8% vs 43.5%, P = .018). Only 4.0% patients received oral anticoagulant (OAC) therapy among AF patients. Moreover, diabetes (26.7%) and dyslipidemia (37.6%) were highly prevalent in AF patients. Furthermore, 212 persons died due to CVD (14.7/1000 person‐years) during a median follow‐up of 3.2 years. AF patients had a 3.42 (95% CI: 2.07‐5.63) times higher risk of CVD mortality than the patients without AF in the fully adjusted model. Therefore, the burden of AF among hypertensive elderly population in northeast China was considerable. Long‐term screening and management strategies for AF and related risk factors are required among hypertensive elderly in northeast China.https://doi.org/10.1111/jch.14483atrial fibrillationcardiovascular diseaseshypertensionmortality
spellingShingle Zhenwei Xia
Wei Dang
Xue Yang
Qun Sun
Jixu Sun
Lei Shi
Shize Sun
Le An
Xiaojing Li
Hongbo Peng
Shuang Liu
Ling Yue
Hongyun Chen
Prevalence of atrial fibrillation and the risk of cardiovascular mortality among hypertensive elderly population in northeast China
The Journal of Clinical Hypertension
atrial fibrillation
cardiovascular diseases
hypertension
mortality
title Prevalence of atrial fibrillation and the risk of cardiovascular mortality among hypertensive elderly population in northeast China
title_full Prevalence of atrial fibrillation and the risk of cardiovascular mortality among hypertensive elderly population in northeast China
title_fullStr Prevalence of atrial fibrillation and the risk of cardiovascular mortality among hypertensive elderly population in northeast China
title_full_unstemmed Prevalence of atrial fibrillation and the risk of cardiovascular mortality among hypertensive elderly population in northeast China
title_short Prevalence of atrial fibrillation and the risk of cardiovascular mortality among hypertensive elderly population in northeast China
title_sort prevalence of atrial fibrillation and the risk of cardiovascular mortality among hypertensive elderly population in northeast china
topic atrial fibrillation
cardiovascular diseases
hypertension
mortality
url https://doi.org/10.1111/jch.14483
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