Single-Nucleotide Polymorphisms in MICA and MICB Genes Could Play a Role in the Outcome in AML Patients after HSCT

Single-Nucleotide Polymorphisms in MICA and MICB Genes Could Play a Role in the Outcome in AML Patients after HSCT

NKG2D and its ligands, MICA and MICB, are known as the key regulators of NK cells. NK cells are the first reconstituted cells after the allogeneic hematopoietic stem cell transplantation (HSCT); therefore, it is crucial to understand their role in HSCT outcome. In the presented study, we investigate...

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Bibliographic Details
Main Authors: Alena Machuldova, Lucie Houdova, Katerina Kratochvilova, Martin Leba, Pavel Jindra, Pavel Ostasov, Diana Maceckova, Robin Klieber, Hana Gmucova, Jiri Sramek, Monika Holubova
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Journal of Clinical Medicine
Subjects:
allogeneic hematopoietic cell transplantation
graft-versus-host disease
graft-versus-tumor effect
NKG2D
MICA
MICB
Online Access:https://www.mdpi.com/2077-0383/10/20/4636

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