The Affect of Pentoxifylline on Sperm Parameters in Normozoospermic, Asthenozoospermic and Oligo-Asthenozoospermic Males
OBJECTIVE: To determine the affect of pentoxifylline (PTX) on sperm parameters in normozoospermic, asthenozoospermic, and oligo-asthenozoospermic males. STUDY DESIGN: Each semen sample collected from normozoospermic (n=20), asthenozoospermic (n=20), and oligo-asthenozoospermic (n=20) males was divid...
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| Format: | Article |
| Language: | English |
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Medical Network
2007-04-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
| Subjects: | |
| Online Access: | http://gorm.com.tr/index.php/GORM/article/view/510 |
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| author | Süheyla Çetintaş İbrahim Esinler Tülay Durak Mesut Öktem Esra Kuşçu Hulusi Zeyneloğlu |
| author_facet | Süheyla Çetintaş İbrahim Esinler Tülay Durak Mesut Öktem Esra Kuşçu Hulusi Zeyneloğlu |
| author_sort | Süheyla Çetintaş |
| collection | DOAJ |
| description | OBJECTIVE: To determine the affect of pentoxifylline (PTX) on sperm parameters in normozoospermic, asthenozoospermic, and oligo-asthenozoospermic males.
STUDY DESIGN: Each semen sample collected from normozoospermic (n=20), asthenozoospermic (n=20), and oligo-asthenozoospermic (n=20) males was divided into two equal parts. One part of the semen sample washed using Puresperm only (NidaCon, Sweden) (After-wash category) and other part was treated with pentoxifylline after washing with Puresperm (PTX-treated category). The semen parameters of the after-wash and PTX-treated categories were compared.
RESULTS: PTX-treated category was demonstrated significant increment of sperm concentration and rate of sperm with intact acrosome (SIA) when compared to after-wash group in both asthenozoospermic and oligo-asthenozoospermic males. In addition, PTX-treated group resulted higher sperm morphology in oligo-asthenozoospermic males when compared to after-wash group. However, PTX did not show any superiority on after-wash group in normozoospermic males.
CONCLUSIONS: Pentoxifylline have beneficial effect on sperm parameters especially in oligo-asthenozoospermic and asthenozoospermic patients. |
| first_indexed | 2024-04-10T14:00:58Z |
| format | Article |
| id | doaj.art-53a55f6394864607a97184957758779f |
| institution | Directory Open Access Journal |
| issn | 1300-4751 |
| language | English |
| last_indexed | 2024-04-10T14:00:58Z |
| publishDate | 2007-04-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj.art-53a55f6394864607a97184957758779f2023-02-15T16:10:15ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512007-04-01131445The Affect of Pentoxifylline on Sperm Parameters in Normozoospermic, Asthenozoospermic and Oligo-Asthenozoospermic MalesSüheyla Çetintaş0İbrahim Esinler1Tülay Durak2Mesut Öktem3Esra Kuşçu4Hulusi Zeyneloğlu5Department of Obstetrics and Gynecology Başkent University Faculty of Medicine, AnkaraDepartment of Obstetrics and Gynecology, Hacettepe University Faculty of Medicine AnkaraDepartment of Obstetrics and Gynecology Başkent University Faculty of Medicine, AnkaraDepartment of Obstetrics and Gynecology Başkent University Faculty of Medicine, AnkaraDepartment of Obstetrics and Gynecology Başkent University Faculty of Medicine, AnkaraDepartment of Obstetrics and Gynecology Başkent University Faculty of Medicine, AnkaraOBJECTIVE: To determine the affect of pentoxifylline (PTX) on sperm parameters in normozoospermic, asthenozoospermic, and oligo-asthenozoospermic males. STUDY DESIGN: Each semen sample collected from normozoospermic (n=20), asthenozoospermic (n=20), and oligo-asthenozoospermic (n=20) males was divided into two equal parts. One part of the semen sample washed using Puresperm only (NidaCon, Sweden) (After-wash category) and other part was treated with pentoxifylline after washing with Puresperm (PTX-treated category). The semen parameters of the after-wash and PTX-treated categories were compared. RESULTS: PTX-treated category was demonstrated significant increment of sperm concentration and rate of sperm with intact acrosome (SIA) when compared to after-wash group in both asthenozoospermic and oligo-asthenozoospermic males. In addition, PTX-treated group resulted higher sperm morphology in oligo-asthenozoospermic males when compared to after-wash group. However, PTX did not show any superiority on after-wash group in normozoospermic males. CONCLUSIONS: Pentoxifylline have beneficial effect on sperm parameters especially in oligo-asthenozoospermic and asthenozoospermic patients.http://gorm.com.tr/index.php/GORM/article/view/510Pentoxifylline, Asthenozoospermia, oligoasthenozoospermia, male infertility, sperm motility, sperm morphology |
| spellingShingle | Süheyla Çetintaş İbrahim Esinler Tülay Durak Mesut Öktem Esra Kuşçu Hulusi Zeyneloğlu The Affect of Pentoxifylline on Sperm Parameters in Normozoospermic, Asthenozoospermic and Oligo-Asthenozoospermic Males Gynecology Obstetrics & Reproductive Medicine Pentoxifylline, Asthenozoospermia, oligoasthenozoospermia, male infertility, sperm motility, sperm morphology |
| title | The Affect of Pentoxifylline on Sperm Parameters in Normozoospermic, Asthenozoospermic and Oligo-Asthenozoospermic Males |
| title_full | The Affect of Pentoxifylline on Sperm Parameters in Normozoospermic, Asthenozoospermic and Oligo-Asthenozoospermic Males |
| title_fullStr | The Affect of Pentoxifylline on Sperm Parameters in Normozoospermic, Asthenozoospermic and Oligo-Asthenozoospermic Males |
| title_full_unstemmed | The Affect of Pentoxifylline on Sperm Parameters in Normozoospermic, Asthenozoospermic and Oligo-Asthenozoospermic Males |
| title_short | The Affect of Pentoxifylline on Sperm Parameters in Normozoospermic, Asthenozoospermic and Oligo-Asthenozoospermic Males |
| title_sort | affect of pentoxifylline on sperm parameters in normozoospermic asthenozoospermic and oligo asthenozoospermic males |
| topic | Pentoxifylline, Asthenozoospermia, oligoasthenozoospermia, male infertility, sperm motility, sperm morphology |
| url | http://gorm.com.tr/index.php/GORM/article/view/510 |
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