Predictive Factors of Sensitivity to Elisidepsin, a Novel Kahalalide F-Derived Marine Compound

Predictive Factors of Sensitivity to Elisidepsin, a Novel Kahalalide F-Derived Marine Compound

Elisidepsin (PM02734, Irvalec®) is a synthetic marine-derived cyclic peptide of the Kahalalide F family currently in phase II clinical development. Elisidepsin was shown to induce rapid oncosis in ErbB3-expressing cells. Other predictive factors of elisidepsin sensitivity remained unknown. A panel o...

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Bibliographic Details
Main Authors: Sandrine Faivre, Eric Raymond, José Jimeno, Miguel Aracil, Ivan Bieche, Carlos Maria Galmarini, Maria Eugenia Riveiro, Maria Serova, Armand de Gramont
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:Marine Drugs
Subjects:
Irvalec
oncosis
E-cadherin
ErbB3
Online Access:http://www.mdpi.com/1660-3397/11/3/944

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