Increased Nitrosoglutathione Reductase Activity in Hypoxic Pulmonary Hypertension in Mice

Altered S-nitrosothiols (RSNO) signaling is linked to pulmonary hypertension. Recent studies have shown that S-nitrosoglutathione (GSNO) reductase (GSNOR) catalyzes the degradation of GSNO and indirectly regulates the level of RSNO in vivo. Our present study tested the hypothesis that chronic hypoxi...

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Bibliografiske detaljer
Main Authors: Xiling Wu, Lizhong Du, Xuefeng Xu, Linhua Tan, Ruyi Li
Format: Article
Sprog:English
Udgivet: Elsevier 2010-01-01
Serier:Journal of Pharmacological Sciences
Online adgang:http://www.sciencedirect.com/science/article/pii/S1347861319309582