Integrating images from multiple microscopy screens reveals diverse patterns of change in the subcellular localization of proteins

The evaluation of protein localization changes on a systematic level is a powerful tool for understanding how cells respond to environmental, chemical, or genetic perturbations. To date, work in understanding these proteomic responses through high-throughput imaging has catalogued localization chang...

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Bibliographic Details
Main Authors: Alex X Lu, Yolanda T Chong, Ian Shen Hsu, Bob Strome, Louis-Francois Handfield, Oren Kraus, Brenda J Andrews, Alan M Moses
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/31872