Conditional Knock out of High-Mobility Group Box 1 (HMGB1) in Rods Reduces Autophagy Activation after Retinal Detachment
After retinal detachment (RD), the induction of autophagy protects photoreceptors (PR) from apoptotic cell death. The cytoplasmic high-mobility group box 1 (HMGB1) promotes autophagy. We previously demonstrated that the deletion of HMGB1 from rod PRs results in a more rapid death of these cells afte...
Main Authors: | Bing X. Ross, Lin Jia, Dejuan Kong, Tiantian Wang, Heather M. Hager, Steven F. Abcouwer, David N. Zacks |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/10/8/2010 |
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