Glycolysis Induces MCJ Expression That Links T Cell Proliferation With Caspase-3 Activity and Death

Glycolysis Induces MCJ Expression That Links T Cell Proliferation With Caspase-3 Activity and Death

An effective adaptive immune response requires rapid T cell proliferation, followed by equally robust cell death. These two processes are coordinately regulated to allow sufficient magnitude of response followed by its rapid resolution, while also providing the maintenance of T cell memory. Both asp...

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Bibliographic Details
Main Authors: Michael A. Secinaro, Karen A. Fortner, Cheryl Collins, Mercedes Rincón, Ralph C. Budd
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
caspase-3
MCJ
glycolysis
T cells
cell death
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00028/full

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