The Dynamic Scleral Extracellular Matrix Alterations in Chronic Ocular Hypertension Model of Rats

The Dynamic Scleral Extracellular Matrix Alterations in Chronic Ocular Hypertension Model of Rats

Intraocular pressure (IOP) generates stress and strains in the laminar cribrosa and sclera, which may affect the development and progression of glaucoma. Scleral stiffness and material components have changed under elevated IOP. However, the detailed changes of the components of the hypertensive scl...

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Bibliographic Details
Main Authors:	Chen Qiu, Jing Yao, Xi Zhang, Rong Zhang, Xinghuai Sun, Shaohong Qian
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-07-01
Series:	Frontiers in Physiology
Subjects:	sclera extracellular matrix matrix metalloproteinase 2 intraocular pressure glaucoma
Online Access:	https://www.frontiersin.org/article/10.3389/fphys.2020.00682/full

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