Effect of stimulation frequency on hippocampal electric field induced by deep-brain magnetic stimulation
Deep-brain Magnetic Stimulation (DMS) is a noninvasive brain modulation method that improves hippocampal neural activity. The frequency of DMS has a significant effect on the hippocampal induced electric field. In this paper, we investigate the relationship between stimulation frequency and DMS-indu...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
AIP Publishing LLC
2023-01-01
|
| Series: | AIP Advances |
| Online Access: | http://dx.doi.org/10.1063/5.0130324 |
| _version_ | 1811172630229680128 |
|---|---|
| author | Xiang-yang Xu Bin Deng Jiang Wang Guo-sheng Yi |
| author_facet | Xiang-yang Xu Bin Deng Jiang Wang Guo-sheng Yi |
| author_sort | Xiang-yang Xu |
| collection | DOAJ |
| description | Deep-brain Magnetic Stimulation (DMS) is a noninvasive brain modulation method that improves hippocampal neural activity. The frequency of DMS has a significant effect on the hippocampal induced electric field. In this paper, we investigate the relationship between stimulation frequency and DMS-induced hippocampal electric field. The frequency sensitivity and distribution uniformity of the hippocampal electric field are calculated to quantify this relationship. The results show that the DMS-induced hippocampal electric field has a frequency-dependent property. The frequency sensitivity of the DMS-induced hippocampal electric field in the high frequency band is lower than that in the low frequency band, which corresponds to the low-pass filtering property of the neuron membrane. The frequency sensitivity of DMS-induced hippocampal electric field is highest in the range of 30–40 Hz. The uniformity of the hippocampal electric field induced by a single coil also reaches the highest in the range of 30–40 Hz, while uniformity of the hippocampal electric field induced by multiple-coil increases with increasing frequency. The frequency-dependent property of the DMS-induced hippocampal electric field is positively correlated with the quantity and size of coils, while negatively correlated with the spacing of the coils. This study is of great help in the selection of DMS frequencies and the design of coils. |
| first_indexed | 2024-04-10T17:33:24Z |
| format | Article |
| id | doaj.art-53b48f5cd82e45dfa0028c5f234f18ab |
| institution | Directory Open Access Journal |
| issn | 2158-3226 |
| language | English |
| last_indexed | 2024-04-10T17:33:24Z |
| publishDate | 2023-01-01 |
| publisher | AIP Publishing LLC |
| record_format | Article |
| series | AIP Advances |
| spelling | doaj.art-53b48f5cd82e45dfa0028c5f234f18ab2023-02-03T16:42:06ZengAIP Publishing LLCAIP Advances2158-32262023-01-01131015012015012-1210.1063/5.0130324Effect of stimulation frequency on hippocampal electric field induced by deep-brain magnetic stimulationXiang-yang Xu0Bin Deng1Jiang Wang2Guo-sheng Yi3School of Electrical and Information Engineering, Tianjin University, Tianjin, ChinaSchool of Electrical and Information Engineering, Tianjin University, Tianjin, ChinaSchool of Electrical and Information Engineering, Tianjin University, Tianjin, ChinaSchool of Electrical and Information Engineering, Tianjin University, Tianjin, ChinaDeep-brain Magnetic Stimulation (DMS) is a noninvasive brain modulation method that improves hippocampal neural activity. The frequency of DMS has a significant effect on the hippocampal induced electric field. In this paper, we investigate the relationship between stimulation frequency and DMS-induced hippocampal electric field. The frequency sensitivity and distribution uniformity of the hippocampal electric field are calculated to quantify this relationship. The results show that the DMS-induced hippocampal electric field has a frequency-dependent property. The frequency sensitivity of the DMS-induced hippocampal electric field in the high frequency band is lower than that in the low frequency band, which corresponds to the low-pass filtering property of the neuron membrane. The frequency sensitivity of DMS-induced hippocampal electric field is highest in the range of 30–40 Hz. The uniformity of the hippocampal electric field induced by a single coil also reaches the highest in the range of 30–40 Hz, while uniformity of the hippocampal electric field induced by multiple-coil increases with increasing frequency. The frequency-dependent property of the DMS-induced hippocampal electric field is positively correlated with the quantity and size of coils, while negatively correlated with the spacing of the coils. This study is of great help in the selection of DMS frequencies and the design of coils.http://dx.doi.org/10.1063/5.0130324 |
| spellingShingle | Xiang-yang Xu Bin Deng Jiang Wang Guo-sheng Yi Effect of stimulation frequency on hippocampal electric field induced by deep-brain magnetic stimulation AIP Advances |
| title | Effect of stimulation frequency on hippocampal electric field induced by deep-brain magnetic stimulation |
| title_full | Effect of stimulation frequency on hippocampal electric field induced by deep-brain magnetic stimulation |
| title_fullStr | Effect of stimulation frequency on hippocampal electric field induced by deep-brain magnetic stimulation |
| title_full_unstemmed | Effect of stimulation frequency on hippocampal electric field induced by deep-brain magnetic stimulation |
| title_short | Effect of stimulation frequency on hippocampal electric field induced by deep-brain magnetic stimulation |
| title_sort | effect of stimulation frequency on hippocampal electric field induced by deep brain magnetic stimulation |
| url | http://dx.doi.org/10.1063/5.0130324 |
| work_keys_str_mv | AT xiangyangxu effectofstimulationfrequencyonhippocampalelectricfieldinducedbydeepbrainmagneticstimulation AT bindeng effectofstimulationfrequencyonhippocampalelectricfieldinducedbydeepbrainmagneticstimulation AT jiangwang effectofstimulationfrequencyonhippocampalelectricfieldinducedbydeepbrainmagneticstimulation AT guoshengyi effectofstimulationfrequencyonhippocampalelectricfieldinducedbydeepbrainmagneticstimulation |