HPV16 E6/E7 promote the translocation and glucose uptake of GLUT1 by PI3K/AKT pathway relieving miR-451 inhibitory effect on CAB39 in lung cancer cells

HPV16 E6/E7 promote the translocation and glucose uptake of GLUT1 by PI3K/AKT pathway relieving miR-451 inhibitory effect on CAB39 in lung cancer cells

Background: HPV16 E6/E7 proteins are the main oncogenes and only long-term persistent infection causes lung cancer. Our previous studies have shown that HPV16 E6/E7 protein up-regulates the expression of GLUT1 in lung cancer cells. However, whether E6 and E7 protein can promote the glucose uptake of...

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Bibliographic Details
Main Authors: Hong-Miao Wang, Ying-Jie Lu, Ling He, Na-Jin Gu, Shi-Yu Wang, Xue-Shan Qiu, En-Hua Wang, Guang-Ping Wu
Format: Article
Language:English
Published: SAGE Publishing 2020-09-01
Series:Therapeutic Advances in Chronic Disease
Online Access:https://doi.org/10.1177/2040622320957143

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