The mechanobiology of nuclear phase separation

The cell nucleus can be thought of as a complex, dynamic, living material, which functions to organize and protect the genome and coordinate gene expression. These functions are achieved via intricate mechanical and biochemical interactions among its myriad components, including the nuclear lamina,...

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Bibliographic Details
Main Authors: Daniel S. W. Lee, Amy R. Strom, Clifford P. Brangwynne
Format: Article
Language:English
Published: AIP Publishing LLC 2022-06-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0083286