Safety and Immunogenicity of a Stable, Cold-Adapted, Temperature-Sensitive/Conditional Lethal Enterovirus A71 in Monkey Study

Safety and Immunogenicity of a Stable, Cold-Adapted, Temperature-Sensitive/Conditional Lethal Enterovirus A71 in Monkey Study

Enterovirus A71 (EV-A71) and coxsackievirus A16 (CA16) are major etiological agents of hand foot and mouth disease (HFMD) in children, which may result in fatal neurological complications. The development of safe, cost effective vaccines against HFMD, especially for use in developing countries, is s...

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Bibliographic Details
Main Authors: Kaw Bing Chua, Qimei Ng, Tao Meng, Qiang Jia
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Viruses
Subjects:
enterovirus A71
coxsackievirus A16
attenuation
temperature sensitive and conditional lethal
candidate vaccine
Online Access:https://www.mdpi.com/1999-4915/13/3/438

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