Microfluidic Mixing: A Physics-Oriented Review

This comprehensive review paper focuses on the intricate physics of microfluidics and their application in micromixing techniques. Various methods for enhancing mixing in microchannels are explored, with a keen emphasis on the underlying fluid dynamics principles. Geometrical micromixers employ comp...

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Main Authors: Sri Manikandan Saravanakumar, Paul-Vahe Cicek
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/14/10/1827
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author Sri Manikandan Saravanakumar
Paul-Vahe Cicek
author_facet Sri Manikandan Saravanakumar
Paul-Vahe Cicek
author_sort Sri Manikandan Saravanakumar
collection DOAJ
description This comprehensive review paper focuses on the intricate physics of microfluidics and their application in micromixing techniques. Various methods for enhancing mixing in microchannels are explored, with a keen emphasis on the underlying fluid dynamics principles. Geometrical micromixers employ complex channel designs to induce fluid–fluid interface distortions, yielding efficient mixing while retaining manufacturing simplicity. These methods synergize effectively with external techniques, showcasing promising potential. Electrohydrodynamics harnesses electrokinetic phenomena like electroosmosis, electrophoresis, and electrothermal effects. These methods offer dynamic control over mixing parameters via applied voltage, frequency, and electrode positioning, although power consumption and heating can be drawbacks. Acoustofluidics leverages acoustic waves to drive microstreaming, offering localized yet far-reaching effects. Magnetohydrodynamics, though limited in applicability to certain fluids, showcases potential by utilizing magnetic fields to propel mixing. Selecting an approach hinges on trade-offs among complexity, efficiency, and compatibility with fluid properties. Understanding the physics of fluid behavior and rationalizing these techniques aids in tailoring the most suitable micromixing solution. In a rapidly advancing field, this paper provides a consolidated understanding of these techniques, facilitating the informed choice of approach for specific microfluidic mixing needs.
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spelling doaj.art-53c36faa90b24eb4931c640076170a422023-11-19T17:23:23ZengMDPI AGMicromachines2072-666X2023-09-011410182710.3390/mi14101827Microfluidic Mixing: A Physics-Oriented ReviewSri Manikandan Saravanakumar0Paul-Vahe Cicek1Microtechnologies Integration & Convergence Research Group, Université du Québec à Montréal (UQAM), Montreal, QC H2X 3Y7, CanadaMicrotechnologies Integration & Convergence Research Group, Université du Québec à Montréal (UQAM), Montreal, QC H2X 3Y7, CanadaThis comprehensive review paper focuses on the intricate physics of microfluidics and their application in micromixing techniques. Various methods for enhancing mixing in microchannels are explored, with a keen emphasis on the underlying fluid dynamics principles. Geometrical micromixers employ complex channel designs to induce fluid–fluid interface distortions, yielding efficient mixing while retaining manufacturing simplicity. These methods synergize effectively with external techniques, showcasing promising potential. Electrohydrodynamics harnesses electrokinetic phenomena like electroosmosis, electrophoresis, and electrothermal effects. These methods offer dynamic control over mixing parameters via applied voltage, frequency, and electrode positioning, although power consumption and heating can be drawbacks. Acoustofluidics leverages acoustic waves to drive microstreaming, offering localized yet far-reaching effects. Magnetohydrodynamics, though limited in applicability to certain fluids, showcases potential by utilizing magnetic fields to propel mixing. Selecting an approach hinges on trade-offs among complexity, efficiency, and compatibility with fluid properties. Understanding the physics of fluid behavior and rationalizing these techniques aids in tailoring the most suitable micromixing solution. In a rapidly advancing field, this paper provides a consolidated understanding of these techniques, facilitating the informed choice of approach for specific microfluidic mixing needs.https://www.mdpi.com/2072-666X/14/10/1827microfluidicsmicromixinglaminar flowmicrodevicesvorticeslab-on-chip
spellingShingle Sri Manikandan Saravanakumar
Paul-Vahe Cicek
Microfluidic Mixing: A Physics-Oriented Review
Micromachines
microfluidics
micromixing
laminar flow
microdevices
vortices
lab-on-chip
title Microfluidic Mixing: A Physics-Oriented Review
title_full Microfluidic Mixing: A Physics-Oriented Review
title_fullStr Microfluidic Mixing: A Physics-Oriented Review
title_full_unstemmed Microfluidic Mixing: A Physics-Oriented Review
title_short Microfluidic Mixing: A Physics-Oriented Review
title_sort microfluidic mixing a physics oriented review
topic microfluidics
micromixing
laminar flow
microdevices
vortices
lab-on-chip
url https://www.mdpi.com/2072-666X/14/10/1827
work_keys_str_mv AT srimanikandansaravanakumar microfluidicmixingaphysicsorientedreview
AT paulvahecicek microfluidicmixingaphysicsorientedreview