Necrotizing Scleritis as a Manifestation of Eosinophilic Granulomatosis With Polyangiitis: A Case Report
Eosinophilic granulomatosis with polyangiitis (EGPA) is an ANCA-associated vasculitis characterized by the development of necrotizing granulomas rich in eosinophils and vasculitis of small and medium vessels, with compromise of the respiratory tract, peripheral nervous system, and least frequent ocu...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2023-03-01
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| Series: | Clinical Medicine Insights: Case Reports |
| Online Access: | https://doi.org/10.1177/11795476231161167 |
| _version_ | 1811154646766452736 |
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| author | Mayra Alejandra Arenas-Beltran Oscar Mauricio Muñoz Velandia |
| author_facet | Mayra Alejandra Arenas-Beltran Oscar Mauricio Muñoz Velandia |
| author_sort | Mayra Alejandra Arenas-Beltran |
| collection | DOAJ |
| description | Eosinophilic granulomatosis with polyangiitis (EGPA) is an ANCA-associated vasculitis characterized by the development of necrotizing granulomas rich in eosinophils and vasculitis of small and medium vessels, with compromise of the respiratory tract, peripheral nervous system, and least frequent ocular involvement. We report the case of a 54-year-old Caucasian man with a history of EGPA who presented ocular pain, red eye, vision loss, and evidence of scleral slimming compatible with necrotizing scleritis. The patient was treated with systemic steroids and cyclophosphamide, which reduced the ocular pain but did not improve visual acuity, needing surgical treatment of the scleral coverage defect. While necrotizing scleritis is an unusual manifestation of EGPA, it should be part of the differential diagnosis in patients with red eye or ocular pain as an accurate diagnosis and prompt treatment could reduce local complications. |
| first_indexed | 2024-04-10T04:19:31Z |
| format | Article |
| id | doaj.art-53c3a356bec34f8bbe809e2144d861f1 |
| institution | Directory Open Access Journal |
| issn | 1179-5476 |
| language | English |
| last_indexed | 2024-04-10T04:19:31Z |
| publishDate | 2023-03-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical Medicine Insights: Case Reports |
| spelling | doaj.art-53c3a356bec34f8bbe809e2144d861f12023-03-11T09:03:27ZengSAGE PublishingClinical Medicine Insights: Case Reports1179-54762023-03-011610.1177/11795476231161167Necrotizing Scleritis as a Manifestation of Eosinophilic Granulomatosis With Polyangiitis: A Case ReportMayra Alejandra Arenas-Beltran0Oscar Mauricio Muñoz Velandia1Internal Medicine Resident, Pontificia Universidad Javeriana, Bogota, ColombiaAttending Professor, Internal Medicine Department, Pontificia Universidad Javeriana, Hospital Universitario San Ignacio, Bogota, ColombiaEosinophilic granulomatosis with polyangiitis (EGPA) is an ANCA-associated vasculitis characterized by the development of necrotizing granulomas rich in eosinophils and vasculitis of small and medium vessels, with compromise of the respiratory tract, peripheral nervous system, and least frequent ocular involvement. We report the case of a 54-year-old Caucasian man with a history of EGPA who presented ocular pain, red eye, vision loss, and evidence of scleral slimming compatible with necrotizing scleritis. The patient was treated with systemic steroids and cyclophosphamide, which reduced the ocular pain but did not improve visual acuity, needing surgical treatment of the scleral coverage defect. While necrotizing scleritis is an unusual manifestation of EGPA, it should be part of the differential diagnosis in patients with red eye or ocular pain as an accurate diagnosis and prompt treatment could reduce local complications.https://doi.org/10.1177/11795476231161167 |
| spellingShingle | Mayra Alejandra Arenas-Beltran Oscar Mauricio Muñoz Velandia Necrotizing Scleritis as a Manifestation of Eosinophilic Granulomatosis With Polyangiitis: A Case Report Clinical Medicine Insights: Case Reports |
| title | Necrotizing Scleritis as a Manifestation of Eosinophilic Granulomatosis With Polyangiitis: A Case Report |
| title_full | Necrotizing Scleritis as a Manifestation of Eosinophilic Granulomatosis With Polyangiitis: A Case Report |
| title_fullStr | Necrotizing Scleritis as a Manifestation of Eosinophilic Granulomatosis With Polyangiitis: A Case Report |
| title_full_unstemmed | Necrotizing Scleritis as a Manifestation of Eosinophilic Granulomatosis With Polyangiitis: A Case Report |
| title_short | Necrotizing Scleritis as a Manifestation of Eosinophilic Granulomatosis With Polyangiitis: A Case Report |
| title_sort | necrotizing scleritis as a manifestation of eosinophilic granulomatosis with polyangiitis a case report |
| url | https://doi.org/10.1177/11795476231161167 |
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