In Silico Searching for Alternative Lead Compounds to Treat Type 2 Diabetes through a QSAR and Molecular Dynamics Study

In Silico Searching for Alternative Lead Compounds to Treat Type 2 Diabetes through a QSAR and Molecular Dynamics Study

Free fatty acid receptor 1 (FFA1) stimulates insulin secretion in pancreatic β-cells. An advantage of therapies that target FFA1 is their reduced risk of hypoglycemia relative to common type 2 diabetes treatments. In this work, quantitative structure–activity relationship (QSAR) approach was used to...

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Bibliographic Details
Main Authors:	Nicolás Cabrera, Sebastián A. Cuesta, José R. Mora, Luis Calle, Edgar A. Márquez, Roland Kaunas, José Luis Paz
Format:	Article
Language:	English
Published:	MDPI AG 2022-01-01
Series:	Pharmaceutics
Subjects:	free fatty acid receptor 1 type 2 diabetes molecular dynamics molecular docking agonits of FFA1
Online Access:	https://www.mdpi.com/1999-4923/14/2/232

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