Drop-on-powder 3D printing of amorphous high dose oral dosage forms: Process development, opportunities and printing limitations

Drop-on-powder 3D printing is able to produce highly drug loaded solid oral dosage forms. However, this technique is mainly limited to well soluble drugs. The majority of pipeline compounds is poorly soluble, though, and requires solubility enhancement, e.g., via formation of amorphous solid dispers...

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Bibliographic Details
Main Authors: Nadine Gottschalk, Alicia Burkard, Julian Quodbach, Malte Bogdahn
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156722000421