Spatiotemporal Regulation of Rho GTPases in Neuronal Migration

Spatiotemporal Regulation of Rho GTPases in Neuronal Migration

Neuronal migration is essential for the orchestration of brain development and involves several contiguous steps: interkinetic nuclear movement (INM), multipolar−bipolar transition, locomotion, and translocation. Growing evidence suggests that Rho GTPases, including RhoA, Rac, Cdc42, and t...

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Bibliographic Details
Main Authors: Zhenyan Xu, Yuewen Chen, Yu Chen
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cells
Subjects:
Rho GTPase
guanine nucleotide exchange factor
GTPase-activating protein
neuronal migration
neuronal development
Online Access:https://www.mdpi.com/2073-4409/8/6/568

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