Long-term stability of ready-to-use epinephrine 0.02 mg/mL injection solution in 50 mL glass vials
In adult intensive care patients, epinephrine is mostly administered by continuous injection with syringe pumps. The objective of this study was to investigate the physicochemical stability of pharmacy prepared ready-to-use epinephrine (E) 0.02 mg/mL injection solutions (total volume 50 mL) for assi...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
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De Gruyter
2022-04-01
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Series: | Pharmaceutical Technology in Hospital Pharmacy |
Subjects: | |
Online Access: | https://doi.org/10.1515/pthp-2021-0015 |
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author | Heeb Rita Marina Erdnüß Frank Reichhold Julia Krämer Irene |
author_facet | Heeb Rita Marina Erdnüß Frank Reichhold Julia Krämer Irene |
author_sort | Heeb Rita Marina |
collection | DOAJ |
description | In adult intensive care patients, epinephrine is mostly administered by continuous injection with syringe pumps. The objective of this study was to investigate the physicochemical stability of pharmacy prepared ready-to-use epinephrine (E) 0.02 mg/mL injection solutions (total volume 50 mL) for assigning shelf-life. |
first_indexed | 2024-04-14T02:36:32Z |
format | Article |
id | doaj.art-53c7f657a6924d679f96a71aa362c4f0 |
institution | Directory Open Access Journal |
issn | 2365-2411 2365-242X |
language | English |
last_indexed | 2024-04-14T02:36:32Z |
publishDate | 2022-04-01 |
publisher | De Gruyter |
record_format | Article |
series | Pharmaceutical Technology in Hospital Pharmacy |
spelling | doaj.art-53c7f657a6924d679f96a71aa362c4f02022-12-22T02:17:25ZengDe GruyterPharmaceutical Technology in Hospital Pharmacy2365-24112365-242X2022-04-0171798910.1515/pthp-2021-0015Long-term stability of ready-to-use epinephrine 0.02 mg/mL injection solution in 50 mL glass vialsHeeb Rita Marina0Erdnüß Frank1Reichhold Julia2Krämer Irene3Department of Pharmacy, University Medical Center Mainz, Johannes Gutenberg-University, Langenbeckstraße 1, D-55131Mainz, GermanyDepartment of Pharmacy, University Medical Center Mainz, Johannes Gutenberg-University, Langenbeckstraße 1, D-55131Mainz, GermanyDepartment of Pharmacy, University Medical Center Mainz, Johannes Gutenberg-University, Langenbeckstraße 1, D-55131Mainz, GermanyDepartment of Pharmacy, University Medical Center Mainz, Johannes Gutenberg-University, Langenbeckstraße 1, D-55131Mainz, GermanyIn adult intensive care patients, epinephrine is mostly administered by continuous injection with syringe pumps. The objective of this study was to investigate the physicochemical stability of pharmacy prepared ready-to-use epinephrine (E) 0.02 mg/mL injection solutions (total volume 50 mL) for assigning shelf-life.https://doi.org/10.1515/pthp-2021-0015adrenaline ready-to-use productepinephrinephysicochemical stability |
spellingShingle | Heeb Rita Marina Erdnüß Frank Reichhold Julia Krämer Irene Long-term stability of ready-to-use epinephrine 0.02 mg/mL injection solution in 50 mL glass vials Pharmaceutical Technology in Hospital Pharmacy adrenaline ready-to-use product epinephrine physicochemical stability |
title | Long-term stability of ready-to-use epinephrine 0.02 mg/mL injection solution in 50 mL glass vials |
title_full | Long-term stability of ready-to-use epinephrine 0.02 mg/mL injection solution in 50 mL glass vials |
title_fullStr | Long-term stability of ready-to-use epinephrine 0.02 mg/mL injection solution in 50 mL glass vials |
title_full_unstemmed | Long-term stability of ready-to-use epinephrine 0.02 mg/mL injection solution in 50 mL glass vials |
title_short | Long-term stability of ready-to-use epinephrine 0.02 mg/mL injection solution in 50 mL glass vials |
title_sort | long term stability of ready to use epinephrine 0 02 mg ml injection solution in 50 ml glass vials |
topic | adrenaline ready-to-use product epinephrine physicochemical stability |
url | https://doi.org/10.1515/pthp-2021-0015 |
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