Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program

Introduction Identifying distinct dimensions of negative symptoms in First Episode Schizophrenia (FES) might result in a better understanding and treatment of this invalidating symptomatology. Objectives Aim of this study was to examine negative symptom structure in FES patients using the Positi...

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Main Authors: L. Pelizza, E. Leuci, D. Maestri, E. Quattrone, G. Paulillo, P. Pellegrini, S. Azzali
Format: Article
Language:English
Published: Cambridge University Press 2021-04-01
Series:European Psychiatry
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S092493382100448X/type/journal_article
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author L. Pelizza
E. Leuci
D. Maestri
E. Quattrone
G. Paulillo
P. Pellegrini
S. Azzali
author_facet L. Pelizza
E. Leuci
D. Maestri
E. Quattrone
G. Paulillo
P. Pellegrini
S. Azzali
author_sort L. Pelizza
collection DOAJ
description Introduction Identifying distinct dimensions of negative symptoms in First Episode Schizophrenia (FES) might result in a better understanding and treatment of this invalidating symptomatology. Objectives Aim of this study was to examine negative symptom structure in FES patients using the Positive and Negative Syndrome Scale (PANSS). Methods All 147 participants, aged 12–35 years, completed the PANSS and the Global Assessment of Functioning (GAF) scale. A principal component analysis with varimax rotation was performed to investigate PANSS negative symptom structure in the FES total sample. Results A 2-factor model (i.e. “Expressive Deficits” and “Asociality” dimensions) was identified. Only “Expressive Deficits” domain had a significant negative correlation with baseline GAF score. Conclusions This bipartite solution seems to be adequate to describe the phenomenological variety of negative symptoms experienced by FES individuals at the point of entry in early intervention services. Disclosure No significant relationships.
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spelling doaj.art-53cb2cc5240645e092864411dda4f0e82023-11-17T05:08:55ZengCambridge University PressEuropean Psychiatry0924-93381778-35852021-04-0164S168S16910.1192/j.eurpsy.2021.448Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” programL. Pelizza0E. Leuci1D. Maestri2E. Quattrone3G. Paulillo4P. Pellegrini5S. Azzali6Department Of Mental Health, Azienda USL di Parma, Parma, ItalyDepartment Of Mental Health, Azienda USL di Parma, Parma, ItalyDepartment Of Mental Health, Azienda USL di Parma, Parma, ItalyDepartment Of Mental Health, Azienda USL di Parma, Parma, ItalyDepartment Of Mental Health, Azienda USL di Parma, Parma, ItalyDepartment Of Mental Health, Azienda USL di Parma, Parma, ItalyDepartment Of Mental Health, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy Introduction Identifying distinct dimensions of negative symptoms in First Episode Schizophrenia (FES) might result in a better understanding and treatment of this invalidating symptomatology. Objectives Aim of this study was to examine negative symptom structure in FES patients using the Positive and Negative Syndrome Scale (PANSS). Methods All 147 participants, aged 12–35 years, completed the PANSS and the Global Assessment of Functioning (GAF) scale. A principal component analysis with varimax rotation was performed to investigate PANSS negative symptom structure in the FES total sample. Results A 2-factor model (i.e. “Expressive Deficits” and “Asociality” dimensions) was identified. Only “Expressive Deficits” domain had a significant negative correlation with baseline GAF score. Conclusions This bipartite solution seems to be adequate to describe the phenomenological variety of negative symptoms experienced by FES individuals at the point of entry in early intervention services. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S092493382100448X/type/journal_articlepsychopathologynegative symptomsschizophréniaearly psychosis
spellingShingle L. Pelizza
E. Leuci
D. Maestri
E. Quattrone
G. Paulillo
P. Pellegrini
S. Azzali
Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program
European Psychiatry
psychopathology
negative symptoms
schizophrénia
early psychosis
title Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program
title_full Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program
title_fullStr Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program
title_full_unstemmed Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program
title_short Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program
title_sort negative symptoms in first episode schizophrenia results from the parma early psychosis program
topic psychopathology
negative symptoms
schizophrénia
early psychosis
url https://www.cambridge.org/core/product/identifier/S092493382100448X/type/journal_article
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