Legionella para-effectors target chromatin and promote bacterial replication

Legionella para-effectors target chromatin and promote bacterial replication

Abstract Legionella pneumophila replicates intracellularly by secreting effectors via a type IV secretion system. One of these effectors is a eukaryotic methyltransferase (RomA) that methylates K14 of histone H3 (H3K14me3) to counteract host immune responses. However, it is not known how L. pneumoph...

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Bibliographic Details
Main Authors: Daniel Schator, Sonia Mondino, Jérémy Berthelet, Cristina Di Silvestre, Mathilde Ben Assaya, Christophe Rusniok, Fernando Rodrigues-Lima, Annemarie Wehenkel, Carmen Buchrieser, Monica Rolando
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37885-z

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https://doi.org/10.1038/s41467-023-37885-z

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