Recent achievements in the management of Raynaud’s phenomenon
Magnus Baumhäkel, Michael BöhmKlinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg/Saar, GermanyAbstract: Raynaud’s phenomenon is a clinical disorder w...
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| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2010-03-01
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| Series: | Vascular Health and Risk Management |
| Online Access: | http://www.dovepress.com/recent-achievements-in-the-management-of-raynaudrsquos-phenomenon-a4157 |
| _version_ | 1818938552662097920 |
|---|---|
| author | Magnus Baumhäkel Michael Böhm |
| author_facet | Magnus Baumhäkel Michael Böhm |
| author_sort | Magnus Baumhäkel |
| collection | DOAJ |
| description | Magnus Baumhäkel, Michael BöhmKlinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg/Saar, GermanyAbstract: Raynaud’s phenomenon is a clinical disorder with episodic digital ischemic vasospasm triggered by cold- or emotional-stress. It was first mentioned by Maurice Raynaud in 1862 describing “a local asphyxia of the extremities” and was further divided into primary Raynaud’s disease and secondary Raynaud’s phenomenon, which is often related to connective tissue diseases, but also physical or chemical strain. Though pathophysiology of Raynaud’s phenomenon is still poorly understood, systemic and local vascular effects are most likely to be involved in primary Raynaud’s disease. In secondary Raynaud’s phenomenon additional abnormalities in vascular structure and function may play the major role. Thus, medical treatment of Raynaud’s phenomenon remains unsatisfactory, due to limited understanding of pathophysiological mechanisms. This review addresses current evidence for medical treatment of primary and secondary Raynaud’s phenomenon with regard to pathophysiological mechanisms as well as future perspectives.Keywords: Raynaud’s disease, mechanisms, treatment |
| first_indexed | 2024-12-20T06:09:40Z |
| format | Article |
| id | doaj.art-53d18f63952543ddae23e7099df31fa1 |
| institution | Directory Open Access Journal |
| issn | 1176-6344 1178-2048 |
| language | English |
| last_indexed | 2024-12-20T06:09:40Z |
| publishDate | 2010-03-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Vascular Health and Risk Management |
| spelling | doaj.art-53d18f63952543ddae23e7099df31fa12022-12-21T19:50:43ZengDove Medical PressVascular Health and Risk Management1176-63441178-20482010-03-012010default207214Recent achievements in the management of Raynaud’s phenomenonMagnus BaumhäkelMichael BöhmMagnus Baumhäkel, Michael BöhmKlinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg/Saar, GermanyAbstract: Raynaud’s phenomenon is a clinical disorder with episodic digital ischemic vasospasm triggered by cold- or emotional-stress. It was first mentioned by Maurice Raynaud in 1862 describing “a local asphyxia of the extremities” and was further divided into primary Raynaud’s disease and secondary Raynaud’s phenomenon, which is often related to connective tissue diseases, but also physical or chemical strain. Though pathophysiology of Raynaud’s phenomenon is still poorly understood, systemic and local vascular effects are most likely to be involved in primary Raynaud’s disease. In secondary Raynaud’s phenomenon additional abnormalities in vascular structure and function may play the major role. Thus, medical treatment of Raynaud’s phenomenon remains unsatisfactory, due to limited understanding of pathophysiological mechanisms. This review addresses current evidence for medical treatment of primary and secondary Raynaud’s phenomenon with regard to pathophysiological mechanisms as well as future perspectives.Keywords: Raynaud’s disease, mechanisms, treatmenthttp://www.dovepress.com/recent-achievements-in-the-management-of-raynaudrsquos-phenomenon-a4157 |
| spellingShingle | Magnus Baumhäkel Michael Böhm Recent achievements in the management of Raynaud’s phenomenon Vascular Health and Risk Management |
| title | Recent achievements in the management of Raynaud’s phenomenon |
| title_full | Recent achievements in the management of Raynaud’s phenomenon |
| title_fullStr | Recent achievements in the management of Raynaud’s phenomenon |
| title_full_unstemmed | Recent achievements in the management of Raynaud’s phenomenon |
| title_short | Recent achievements in the management of Raynaud’s phenomenon |
| title_sort | recent achievements in the management of raynaud amp rsquo s phenomenon |
| url | http://www.dovepress.com/recent-achievements-in-the-management-of-raynaudrsquos-phenomenon-a4157 |
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