Differential denaturation of serum proteome reveals a significant amount of hidden information in complex mixtures of proteins.

Differential denaturation of serum proteome reveals a significant amount of hidden information in complex mixtures of proteins.

UNLABELLED: Recently developed proteomic technologies allow to profile thousands of proteins within a high-throughput approach towards biomarker discovery, although results are not as satisfactory as expected. In the present study we demonstrate that serum proteome denaturation is a key underestimat...

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Bibliographic Details
Main Authors: Vincenzo Verdoliva, Cinzia Senatore, Maria Letizia Polci, Stefania Rossi, Martina Cordella, Giuseppe Carlucci, Paolo Marchetti, Giancarlo Antonini-Cappellini, Antonio Facchiano, Daniela D'Arcangelo, Francesco Facchiano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3606341?pdf=render

Internet

http://europepmc.org/articles/PMC3606341?pdf=render

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