The Evolution of the 3D-Printed Drug Delivery Systems: A Review
Since the appearance of the 3D printing in the 1980s it has revolutionized many research fields including the pharmaceutical industry. The main goal is to manufacture complex, personalized products in a low-cost manufacturing process on-demand. In the last few decades, 3D printing has attracted the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4923/14/7/1312 |
| _version_ | 1827618711207411712 |
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| author | Ildikó Bácskay Zoltán Ujhelyi Pálma Fehér Petra Arany |
| author_facet | Ildikó Bácskay Zoltán Ujhelyi Pálma Fehér Petra Arany |
| author_sort | Ildikó Bácskay |
| collection | DOAJ |
| description | Since the appearance of the 3D printing in the 1980s it has revolutionized many research fields including the pharmaceutical industry. The main goal is to manufacture complex, personalized products in a low-cost manufacturing process on-demand. In the last few decades, 3D printing has attracted the attention of numerous research groups for the manufacturing of different drug delivery systems. Since the 2015 approval of the first 3D-printed drug product, the number of publications has multiplied. In our review, we focused on summarizing the evolution of the produced drug delivery systems in the last 20 years and especially in the last 5 years. The drug delivery systems are sub-grouped into tablets, capsules, orodispersible films, implants, transdermal delivery systems, microneedles, vaginal drug delivery systems, and micro- and nanoscale dosage forms. Our classification may provide guidance for researchers to more easily examine the publications and to find further research directions. |
| first_indexed | 2024-03-09T10:13:20Z |
| format | Article |
| id | doaj.art-53dfcdd3ba0d4d6fb5d12424212cd696 |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-09T10:13:20Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-53dfcdd3ba0d4d6fb5d12424212cd6962023-12-01T22:33:54ZengMDPI AGPharmaceutics1999-49232022-06-01147131210.3390/pharmaceutics14071312The Evolution of the 3D-Printed Drug Delivery Systems: A ReviewIldikó Bácskay0Zoltán Ujhelyi1Pálma Fehér2Petra Arany3Healthcare Industry Institute, University of Debrecen, Nagyerdei körút 98, H-4032 Debrecen, HungaryDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, Nagyerdei körút 98, H-4032 Debrecen, HungaryDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, Nagyerdei körút 98, H-4032 Debrecen, HungaryHealthcare Industry Institute, University of Debrecen, Nagyerdei körút 98, H-4032 Debrecen, HungarySince the appearance of the 3D printing in the 1980s it has revolutionized many research fields including the pharmaceutical industry. The main goal is to manufacture complex, personalized products in a low-cost manufacturing process on-demand. In the last few decades, 3D printing has attracted the attention of numerous research groups for the manufacturing of different drug delivery systems. Since the 2015 approval of the first 3D-printed drug product, the number of publications has multiplied. In our review, we focused on summarizing the evolution of the produced drug delivery systems in the last 20 years and especially in the last 5 years. The drug delivery systems are sub-grouped into tablets, capsules, orodispersible films, implants, transdermal delivery systems, microneedles, vaginal drug delivery systems, and micro- and nanoscale dosage forms. Our classification may provide guidance for researchers to more easily examine the publications and to find further research directions.https://www.mdpi.com/1999-4923/14/7/13123D printingdrug delivery systemstabletimplantTTSmicroneedle |
| spellingShingle | Ildikó Bácskay Zoltán Ujhelyi Pálma Fehér Petra Arany The Evolution of the 3D-Printed Drug Delivery Systems: A Review Pharmaceutics 3D printing drug delivery systems tablet implant TTS microneedle |
| title | The Evolution of the 3D-Printed Drug Delivery Systems: A Review |
| title_full | The Evolution of the 3D-Printed Drug Delivery Systems: A Review |
| title_fullStr | The Evolution of the 3D-Printed Drug Delivery Systems: A Review |
| title_full_unstemmed | The Evolution of the 3D-Printed Drug Delivery Systems: A Review |
| title_short | The Evolution of the 3D-Printed Drug Delivery Systems: A Review |
| title_sort | evolution of the 3d printed drug delivery systems a review |
| topic | 3D printing drug delivery systems tablet implant TTS microneedle |
| url | https://www.mdpi.com/1999-4923/14/7/1312 |
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