The relationship of reproductive factors with adiposity and body shape indices changes overtime: findings from a community-based study
Abstract Background Studies focusing on the relationships of adiposity and body shape indices with reproductive factors have reported conflicting results. This study aimed to investigate the influence of reproductive factors on adiposity and body shape indices changes overtime. Materials and methods...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-02-01
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| Series: | Journal of Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12967-023-04000-1 |
| _version_ | 1797863670939648000 |
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| author | Mina Amiri Maryam Mousavi Fereidoun Azizi Fahimeh Ramezani Tehrani |
| author_facet | Mina Amiri Maryam Mousavi Fereidoun Azizi Fahimeh Ramezani Tehrani |
| author_sort | Mina Amiri |
| collection | DOAJ |
| description | Abstract Background Studies focusing on the relationships of adiposity and body shape indices with reproductive factors have reported conflicting results. This study aimed to investigate the influence of reproductive factors on adiposity and body shape indices changes overtime. Materials and methods In this community-based prospective study, 1636 postmenopausal women were selected from Tehran Lipid and Glucose Study (TLGS). The unadjusted and adjusted Generalized Estimating Equation models (GEE) were applied to investigate secular longitudinal trends of adiposity and body shape indices. Results According to the adjusted GEE models, mean changes in body mass index (BMI) in women with early menarche was 1.18 kg/m2 higher than those with normal menarche age (P = 0.030). Moreover, the mean changes in BMI overtime were 0.11 kg/m2 higher in women with premature/early menopausal age than those with normal menopausal age (P = 0.012). Mean changes of waist circumference (WC) in women with late menopause were 2.27 cm higher than those with normal menopausal age (P = 0.036). We also observed higher mean changes in a body shape index (ABSI) in women with late menopause (P = 0.037), compared to those with normal menopausal age. We found a marginal effect of parity on BMI and WC as well. Conclusions This study demonstrated higher BMI in females with earlier menarche age. We also showed higher values of BMI overtime in women with premature/ early menopause, whereas women with late menopausal age had higher WC and ABSI values. However, more longitudinal studies investigating body composition indices by adjusting all potential confounders are still required to confirm our study findings. |
| first_indexed | 2024-04-09T22:40:24Z |
| format | Article |
| id | doaj.art-53e3ef76520144ce9aea676dc478a362 |
| institution | Directory Open Access Journal |
| issn | 1479-5876 |
| language | English |
| last_indexed | 2024-04-09T22:40:24Z |
| publishDate | 2023-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Translational Medicine |
| spelling | doaj.art-53e3ef76520144ce9aea676dc478a3622023-03-22T12:13:34ZengBMCJournal of Translational Medicine1479-58762023-02-0121111310.1186/s12967-023-04000-1The relationship of reproductive factors with adiposity and body shape indices changes overtime: findings from a community-based studyMina Amiri0Maryam Mousavi1Fereidoun Azizi2Fahimeh Ramezani Tehrani3Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesReproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesEndocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesReproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesAbstract Background Studies focusing on the relationships of adiposity and body shape indices with reproductive factors have reported conflicting results. This study aimed to investigate the influence of reproductive factors on adiposity and body shape indices changes overtime. Materials and methods In this community-based prospective study, 1636 postmenopausal women were selected from Tehran Lipid and Glucose Study (TLGS). The unadjusted and adjusted Generalized Estimating Equation models (GEE) were applied to investigate secular longitudinal trends of adiposity and body shape indices. Results According to the adjusted GEE models, mean changes in body mass index (BMI) in women with early menarche was 1.18 kg/m2 higher than those with normal menarche age (P = 0.030). Moreover, the mean changes in BMI overtime were 0.11 kg/m2 higher in women with premature/early menopausal age than those with normal menopausal age (P = 0.012). Mean changes of waist circumference (WC) in women with late menopause were 2.27 cm higher than those with normal menopausal age (P = 0.036). We also observed higher mean changes in a body shape index (ABSI) in women with late menopause (P = 0.037), compared to those with normal menopausal age. We found a marginal effect of parity on BMI and WC as well. Conclusions This study demonstrated higher BMI in females with earlier menarche age. We also showed higher values of BMI overtime in women with premature/ early menopause, whereas women with late menopausal age had higher WC and ABSI values. However, more longitudinal studies investigating body composition indices by adjusting all potential confounders are still required to confirm our study findings.https://doi.org/10.1186/s12967-023-04000-1AdiposityBody mass index (BMI)Waist circumference (WC)A body shape index (ABSI)Age at menarcheAge at menopause |
| spellingShingle | Mina Amiri Maryam Mousavi Fereidoun Azizi Fahimeh Ramezani Tehrani The relationship of reproductive factors with adiposity and body shape indices changes overtime: findings from a community-based study Journal of Translational Medicine Adiposity Body mass index (BMI) Waist circumference (WC) A body shape index (ABSI) Age at menarche Age at menopause |
| title | The relationship of reproductive factors with adiposity and body shape indices changes overtime: findings from a community-based study |
| title_full | The relationship of reproductive factors with adiposity and body shape indices changes overtime: findings from a community-based study |
| title_fullStr | The relationship of reproductive factors with adiposity and body shape indices changes overtime: findings from a community-based study |
| title_full_unstemmed | The relationship of reproductive factors with adiposity and body shape indices changes overtime: findings from a community-based study |
| title_short | The relationship of reproductive factors with adiposity and body shape indices changes overtime: findings from a community-based study |
| title_sort | relationship of reproductive factors with adiposity and body shape indices changes overtime findings from a community based study |
| topic | Adiposity Body mass index (BMI) Waist circumference (WC) A body shape index (ABSI) Age at menarche Age at menopause |
| url | https://doi.org/10.1186/s12967-023-04000-1 |
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